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Titolo:
The value of ultrasound-guided fine-needle aspiration cytology for thyroidnodules: An assessment of its diagnostic potential and pitfalls
Autore:
Ogawa, Y; Kato, Y; Ikeda, K; Aya, M; Ogisawa, K; Kitani, K; Onoda, N; Ishikawa, T; Haba, T; Wakasa, H; Hirakawa, K;
Indirizzi:
Osaka City Univ, Sch Med, Dept Surg 1, Abeno Ku, Osaka 5458585, Japan Osaka City Univ Osaka Japan 5458585 rg 1, Abeno Ku, Osaka 5458585, Japan
Titolo Testata:
SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY
fascicolo: 2, volume: 31, anno: 2001,
pagine: 97 - 101
SICI:
0941-1291(2001)31:2<97:TVOUFA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
LESIONS; MANAGEMENT; BIOPSY;
Keywords:
ultrasound; fine-needle aspiration; cytology; thyroid;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Ogawa, Y Osaka City Univ, Sch Med, Dept Surg 1, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, Japan Osaka City Univ 1-4-3 Asahi Machi Osaka Japan 5458585 585, Japan
Citazione:
Y. Ogawa et al., "The value of ultrasound-guided fine-needle aspiration cytology for thyroidnodules: An assessment of its diagnostic potential and pitfalls", SURG TODAY, 31(2), 2001, pp. 97-101

Abstract

This study was conducted to assess the diagnostic potential and pitfalls of performing fine-needle aspiration cytology (FNAC) for thyroid nodules. Weretrospectively analyzed 1012 aspirated samples obtained from 806 thyroid nodules by the ultrasound (US)-guided method. Of these 806 nodules, 226 (31%) had been surgically treated, 152 (67%) of which were histologically diagnosed as malignant. The rate of sufficient aspirate was 82%, being lower innodules with a diameter of less than 5 mm (73%, P = 0.10); either calcified (77%, P = 0.043) or benign (72%, P = 0.0002). The accuracy of FNAC was 75%, the rate of indeterminate diagnosis was 16%, the false negative rate was13%, and the positive malignancy rate was 99%. The rate of indeterminate diagnosis was higher in adenomatous goiter, follicular carcinoma, and malignant lymphoma, at P = 0.015, P = 0.0008, and P = 0.035, respectively. The accuracy was lower in follicular carcinoma and malignant lymphoma (both at P = 0.013). Sufficient aspirate was finally obtained from 701 (87%) of the 806 nodules by repeated aspiration. Of 152 malignant nodules, 28 (18%) were diagnosed after two or more aspirations, and the accuracy was improved to 81% by repeating the procedure. These findings indicated that repeated aspiration may be a simple and effective method of improving the diagnostic potential of FNAC.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 12:11:28