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Titolo:
The cell biology of neuronal navigation
Autore:
Song, HJ; Poo, MM;
Indirizzi:
Salk Inst Biol Studies, Mol Neurobiol Lab, La Jolla, CA 92037 USA Salk Inst Biol Studies La Jolla CA USA 92037 Lab, La Jolla, CA 92037 USA Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA Univ Calif Berkeley Berkeley CA USA 94720 ll Biol, Berkeley, CA 94720 USA
Titolo Testata:
NATURE CELL BIOLOGY
fascicolo: 3, volume: 3, anno: 2001,
pagine: E81 - E88
SICI:
1465-7392(200103)3:3<E81:TCBONN>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
GROWTH CONE GUIDANCE; CENTRAL-NERVOUS-SYSTEM; AXON GUIDANCE; NEUTROPHIL CHEMOTAXIS; SIGNAL-TRANSDUCTION; CEREBRAL-CORTEX; MAMMALIAN BRAIN; LEADING-EDGE; MIGRATION; CHEMOATTRACTANT;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
100
Recensione:
Indirizzi per estratti:
Indirizzo: Song, HJ Salk Inst Biol Studies, Mol Neurobiol Lab, La Jolla, CA 92037 USASalk Inst Biol Studies La Jolla CA USA 92037 Jolla, CA 92037 USA
Citazione:
H.J. Song e M.M. Poo, "The cell biology of neuronal navigation", NAT CELL BI, 3(3), 2001, pp. E81-E88

Abstract

Morphogenesis of the nervous system requires the directed migration of postmitotic neurons to designated locations in the nervous system and the guidance of axon growth cones to their synaptic targets. Evidence suggests thatboth forms of navigation depend on common guidance molecules, surface receptors and signal transduction pathways that link receptor activation to cytoskeletal reorganization. Future challenges remain not only in identifying all the components of the signalling pathways, but also in understanding how these pathways achieve signal amplification and adaptation-two essential cellular processes for neuronal navigation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 09:25:35