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Titolo:
Graafian follicle function and luteinization in nonprimates
Autore:
Richards, JS;
Indirizzi:
Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 Cellular Biol, Houston, TX 77030 USA
Titolo Testata:
JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION
fascicolo: 1, volume: 8, anno: 2001, supplemento:, S
pagine: S21 - S23
SICI:
1071-5576(200101/02)8:1<S21:GFFALI>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
OVARIAN GRANULOSA-CELLS; HORMONAL-CONTROL; INDUCED KINASE; EXPRESSION; DIFFERENTIATION; PROLIFERATION; ACTIVATION; FAMILY; CYCLE; RAP1;
Keywords:
FSH; LH; IGF; proliferation; ovulation; luteinization; cyclin D2; PKB; SGK; cathepsin L; ADAMTS-1;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Richards, JS Baylor Coll Med, Dept Mol & Cellular Biol, 1 Baylor Plaza, Houston, TX 77030 USA Baylor Coll Med 1 Baylor Plaza Houston TX USA 77030 77030 USA
Citazione:
J.S. Richards, "Graafian follicle function and luteinization in nonprimates", J SOC GYN I, 8(1), 2001, pp. S21-S23

Abstract

The ovarian follicle has two major functions. It provides for the maturation and release of a fertilizable oocyte. It also forms the corpus luteum, which promotes and maintains implantation of the embryo. For these processesto occur, the follicle has to grow, ovulate, and luteinize. The transitionof granulosa cells to luteal cells requires rapid changes in the expression of specific genes. In this transition, many genes expressed in granulosa cells are turned off, whereas the genes controlling terminal differentiation to luteal cells are induced. Of major importance are changes in the regulation of specific kinase cascades that regulate proliferation and differentiation as well as specific protease cascades that control the remodeling ofthe follicle during ovulation and formation of the corpus luteum. The dramatic reprogramming of gene expression in granulosa cells leading to that ofluteal cells is complete within 5 to 7 hours and is irreversible. (J Soc Gynecol Investig 2001;8:S21-S23) Copyright (C) 2001 by the Society for Gynecologic Investigation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 09:23:44