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Titolo:
Retinol-binding protein in idiopathic intracranial hypertension (IIH)
Autore:
Selhorst, JB; Kulkantrakorn, K; Corbett, JJ; Leira, EC; Chung, SM;
Indirizzi:
St Louis Univ, Hlth Sci Ctr, Dept Neurol, Sch Med, St Louis, MO 63110 USA St Louis Univ St Louis MO USA 63110 urol, Sch Med, St Louis, MO 63110 USA St Louis Univ, Sch Med, Dept Ophthalmol, St Louis, MO 63110 USA St Louis Univ St Louis MO USA 63110 pt Ophthalmol, St Louis, MO 63110 USA Univ Mississippi, Dept Neurol, Jackson, MS 39216 USA Univ Mississippi Jackson MS USA 39216 Dept Neurol, Jackson, MS 39216 USA Univ Mississippi, Dept Ophthalmol, Jackson, MS 39216 USA Univ MississippiJackson MS USA 39216 t Ophthalmol, Jackson, MS 39216 USA
Titolo Testata:
JOURNAL OF NEURO-OPHTHALMOLOGY
fascicolo: 4, volume: 20, anno: 2000,
pagine: 250 - 252
SICI:
1070-8022(200012)20:4<250:RPIIIH>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
VITAMIN-A; PSEUDOTUMOR CEREBRI; TRANSPORT; HYPERVITAMINOSIS; ABSORPTION; PRESSURE; STORAGE; BLOOD; LIVER;
Keywords:
idiopathic intracranial hypertension; obesity; pseudotumor cerebri; retinol-binding protein; vitamin A;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Selhorst, JB St Louis Univ, Hlth Sci Ctr, Dept Neurol, Sch Med, 3635 Vista& Grand Blvd, St Louis, MO 63110 USA St Louis Univ 3635 Vista & Grand BlvdSt Louis MO USA 63110 A
Citazione:
J.B. Selhorst et al., "Retinol-binding protein in idiopathic intracranial hypertension (IIH)", J NEURO-OPH, 20(4), 2000, pp. 250-252

Abstract

Objective: We postulated that an alteration in endogenous vitamin A (retinol) metabolism plays a causal role in the pathogenesis of idiopathic intracranial hypertension (IIH). Materials and Methods: Serum retinol was determined by a fluorometric method from 40 control subjects and 58 patients with idiopathic intracranial hypertension (IIH). Retinol binding protein (RBP) was also assayed by quantitative radial immunodiffusion in 17 control subjects and 30 patients with IIH. Results: Mean retinol values were higher in the IIH group compared with the control group, but did not reach a significant level. However, seven of 30 patients with IIH had high REP levels, but none of the control subjects did. Conclusion: This data suggests that IIH is associated with an abnormality in vitamin A metabolism that is linked to its transport system.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 11:18:25