Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Relation between size at birth and age-related cataract
Autore:
Hall, NF; Gale, CR; Syddall, H; Martyn, CN; Phillips, DIW;
Indirizzi:
Univ Southampton, MRC, Environm Epidemiol Unit, Southampton SO9 5NH, Hants, England Univ Southampton Southampton Hants England SO9 5NH O9 5NH, Hants, England
Titolo Testata:
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
fascicolo: 3, volume: 42, anno: 2001,
pagine: 614 - 619
SICI:
0146-0404(200103)42:3<614:RBSABA>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
BEAVER DAM EYE; CLASSIFICATION-SYSTEM-III; BLUE MOUNTAINS EYE; LENS OPACITIES; RISK-FACTORS; NUCLEAR CATARACTS; FETAL GROWTH; MAJOR GENE; IN-UTERO; PREVALENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Hall, NF Univ Southampton, Southampton Gen Hosp, Environm Epidemiol Unit, MRC, Tremona Rd, Southampton S016 6YD, Hants, England Univ Southampton Tremona Rd Southampton Hants England S016 6YD nd
Citazione:
N.F. Hall et al., "Relation between size at birth and age-related cataract", INV OPHTH V, 42(3), 2001, pp. 614-619

Abstract

PURPOSE. TO determine whether poor fetal growth, as determined by size at birth, is associated with an increased risk of age-related cataract. METHODS. A total of 741 men and women born in Sheffield, England between 1922 and 1930 and whose size at birth was available were traced and invited to take part in the study. Of these, 392 (53%) attended for ophthalmic examination. Lens opacity in these volunteers was graded using the Lens Opacities Classification System (LOCS) III. RESULTS. After adjusting for age, gender, gestational age, and risk factors for cataract there were no consistent associations between size at birth and age-related cataract. However, the odds ratio for nuclear cataract (opalescence) among subjects whose birth weight was more than 8 lb was 2.4 (95%CI 1.2 to 5.0) compared with those who weighed under 6 lb 12 oz at birth. Risk of cortical cataract by contrast fell with increasing birth weight, but the trend was not significant and became weak after adjusting for gestational age and other risk factors for cataract. No relation was evident between risk of posterior subcapsular cataract and size at birth. CONCLUSIONS. There is no consistent association between size at birth and age-related cataract. The higher risk of nuclear cataract with increased birth weight was contrary to the expected trend. The apparent difference in direction of the relation between birth weight and different subtypes of cataract may be a chance finding but warrants further exploration.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 07:55:29