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Titolo:
Improving PET-based physiological quantification through methods of wavelet denoising
Autore:
Lin, JW; Laine, AF; Bergmann, SR;
Indirizzi:
Columbia Univ, Dept Biomed Engn, New York, NY 10027 USA Columbia Univ NewYork NY USA 10027 t Biomed Engn, New York, NY 10027 USA Natl Taiwan Univ Hosp, Dept Med, Taipei 106, Taiwan Natl Taiwan Univ HospTaipei Taiwan 106 sp, Dept Med, Taipei 106, Taiwan Columbia Univ, Coll Phys & Surg, Div Cardiol, Dept Med, New York, NY 10027USA Columbia Univ New York NY USA 10027 diol, Dept Med, New York, NY 10027USA Columbia Univ, Coll Phys & Surg, Dept Radiol, New York, NY 10027 USA Columbia Univ New York NY USA 10027 , Dept Radiol, New York, NY 10027 USA
Titolo Testata:
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
fascicolo: 2, volume: 48, anno: 2001,
pagine: 202 - 212
SICI:
0018-9294(200102)48:2<202:IPPQTM>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; MYOCARDIAL BLOOD-FLOW; NONINVASIVE QUANTIFICATION; CONTRAST ENHANCEMENT; N-13 AMMONIA; DYNAMIC PET; RB-82; MODEL; (H2O)-O-15; SHRINKAGE;
Keywords:
multidimensional analysis; myocardial perfusion; positron emission tomography; wavelet denoising;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Engineering, Computing & Technology
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Laine, AF Columbia Univ, Dept Biomed Engn, CEPSR Bldg,Room 416,530 W 120thSt,MC 8904, New York, NY 10027 USA Columbia Univ CEPSR Bldg,Room 416,530 W120th St,MC 8904 New York NY USA 10027
Citazione:
J.W. Lin et al., "Improving PET-based physiological quantification through methods of wavelet denoising", IEEE BIOMED, 48(2), 2001, pp. 202-212

Abstract

The goal of this study was to evaluate methods of multidimensional waveletdenoising on restoring the fidelity of biological signals hidden within dynamic positron emission tomography (PET) images. A reduction of noise within pixels, between adjacent regions, and time-serial frames was achieved viaredundant multiscale representations. In analyzing dynamic PET data of healthy volunteers, a multiscale method improved the estimate-to-error ratio of flows fivefold without loss of detail. This technique also maintained accuracy of now estimates in comparison with the "gold standard," using dynamic PET with O15-water. In addition, in studies of coronary disease patients, now patterns were preserved and infarcted regions were well differentiated from normal regions. The results show that a wavelet-based noise-suppression method produced reliable approximations of salient underlying signals and led to an accurate quantification of myocardial perfusion. The described protocol can be generalized to other temporal biomedical imaging modalities including functionalmagnetic resonance imaging and ultrasound.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 07:25:06