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Titolo:
Low HDL-cholesterol: A component of the metabolic syndrome only in the presence of fasting hypertriglyceridemia in type 2 diabetic patients
Autore:
Bo, S; Cavallo-Perin, P; Gentile, L; Repetti, E; Pagano, G;
Indirizzi:
Univ Turin, Dipartimento Med Interna, I-10126 Turin, Italy Univ Turin Turin Italy I-10126 timento Med Interna, I-10126 Turin, Italy Hosp Asti, Dept Internal Med, Diabet Clin, Trent, Italy Hosp Asti Trent Italy sti, Dept Internal Med, Diabet Clin, Trent, Italy
Titolo Testata:
DIABETES & METABOLISM
fascicolo: 1, volume: 27, anno: 2001,
pagine: 31 - 35
SICI:
1262-3636(200102)27:1<31:LHACOT>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEART-DISEASE MORTALITY; INSULIN-RESISTANT STATE; MELLITUS; MEN;
Keywords:
isolated low HDL-cholesterol; metabolic syndrome; fasting hypertriglyceridemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Bo, S Univ Turin, Dipartimento Med Interna, Cso AM Dogliotti 14, I-10126 Turin, Italy Univ Turin Cso AM Dogliotti 14 Turin Italy I-10126 126 Turin, Italy
Citazione:
S. Bo et al., "Low HDL-cholesterol: A component of the metabolic syndrome only in the presence of fasting hypertriglyceridemia in type 2 diabetic patients", DIABETE MET, 27(1), 2001, pp. 31-35

Abstract

The relation between isolated low HDL-cholesterol and the components of the metabolic syndrome is poorly known in type 2 diabetes. We evaluated cardiovascular risk parameters in type 2 diabetic patients with low HDL-cholesterol, compared to those with low HDL-cholesterol and hypertriglyceridemia, isolated hypertriglyceridemia and normal lipid parameters. Patients with lowHDL-cholesterol/high triglycerides had higher BMI (29.6 +/- 5.7 vs 27.9 +/- 4.4 or vs 28.1 +/- 5.2 kg/m(2)), prevalence of obesity (69% vs 55% or vs 54%), higher levels of uric acid (339.0 +/- 83.3 vs 303.3 +/- 95.2 or vs 303.3 +/- 89.2 mu mol/l) and C-peptide (0.76 +/- 0.40 vs 0.63 +/- 0.33 or vs 0.63 +/- 0.36 nmol/l) and number of components of the metabolic syndrome (27% patients with all the components) compared to patients with isolated lowHDL-cholesterol or normal subjects, respectively. A similar pattern of values was evident in patients with isolated hypertriglyceridemia. With logistic regression analysis, BMI and uric acid levels were significantly associated with the presence of hypertriglyceridemia (both isolated or associated with low HDL-cholesterol), while patients with isolated low HDL-cholesteroland those without dyslipidemia displayed a similar more favourable metabolic pattern. These results indicate that low HDL-cholesterol is a component of the metabolic syndrome only in the presence of fasting hypertriglyceridemia in type 2 diabetic patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 08:56:55