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Titolo:
Normobaric hyperoxic stress in budgerigars: non-enzymic antioxidants
Autore:
Jaensch, S; Cullen, L; Morton, L; Raidal, SR;
Indirizzi:
Murdoch Univ, Div Vet & Biomed Sci, Murdoch, WA 6150, Australia Murdoch Univ Murdoch WA Australia 6150 d Sci, Murdoch, WA 6150, Australia Univ Western Australia, Dept Med, Perth, WA 6847, Australia Univ Western Australia Perth WA Australia 6847 Perth, WA 6847, Australia
Titolo Testata:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
fascicolo: 2, volume: 128, anno: 2001,
pagine: 181 - 187
SICI:
1532-0456(200102)128:2<181:NHSIBN>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Keywords:
avian; oxygen toxicity; pulmonary; normobaric; glutathione; tocopherol; carotenoid; uric acid;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Jaensch, S Murdoch Univ, Div Vet & Biomed Sci, South St, Murdoch, WA 6150,Australia Murdoch Univ South St Murdoch WA Australia 6150 6150, Australia
Citazione:
S. Jaensch et al., "Normobaric hyperoxic stress in budgerigars: non-enzymic antioxidants", COMP BIOC C, 128(2), 2001, pp. 181-187

Abstract

The effects of oxygen exposure on pulmonary and blood non-enzymic antioxidant concentrations was evaluated in budgerigars (Melopsittacus undulatus). Budgerigars were exposed to acute (3 h), repeated acute (3 exposures each of 3 h) or chronic (72 h) normobaric hyperoxic environments and the pulmonary and plasma concentrations of selected non-enzymic antioxidants, namely glutathione, uric acid, alpha and gamma -tocopherol and carotenoids were assayed. With increasing duration of oxygen exposure, the ratio of oxidised to reduced glutathione was significantly increased, while the concentrations of uric acid, alpha - and gamma -tocopherol and carotenoids were significantly reduced, especially following chronic oxygen exposure. Following acute and repeated acute exposure, alteration in glutathione concentrations and reduction in cr-tocopherol concentrations indicated oxygen stress. Following chronic exposure, depletion of non-enzymic antioxidants indicated exhaustion of these protective mechanisms and progression from oxygen stress to oxygen toxicity. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 10:05:26