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Titolo:
Catheter-based electromechanical mapping to assess regional myocardial function: A comparative analysis with transthoracic echocardiography
Autore:
Kornowski, R; Fuchs, S; Shiran, A; Summers, N; Pietrusewicz, M; Ellahham, S; Goldstein, SA; Leon, MB;
Indirizzi:
Washington Hosp Ctr, Cardiovasc Res Inst, Washington, DC 20010 USA Washington Hosp Ctr Washington DC USA 20010 nst, Washington, DC 20010 USA Cardiovasc Data Anal Ctr, Boston, MA USA Cardiovasc Data Anal Ctr Boston MA USA asc Data Anal Ctr, Boston, MA USA Lenox Hill Hosp, Cardiovasc Res Fdn, New York, NY 10021 USA Lenox Hill Hosp New York NY USA 10021 asc Res Fdn, New York, NY 10021 USA
Titolo Testata:
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
fascicolo: 3, volume: 52, anno: 2001,
pagine: 342 - 347
SICI:
1522-1946(200103)52:3<342:CEMTAR>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
INFARCTION; MODEL;
Keywords:
left ventricular mapping; ischemia; echocardiography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Kornowski, R Washington Hosp Ctr, Cardiovasc Res Inst, 110 Irving St NW,4B-1, Washington, DC 20010 USA Washington Hosp Ctr 110 Irving St NW,4B-1 Washington DC USA 20010
Citazione:
R. Kornowski et al., "Catheter-based electromechanical mapping to assess regional myocardial function: A comparative analysis with transthoracic echocardiography", CATHET C IN, 52(3), 2001, pp. 342-347

Abstract

Recent studies using a nonfluoroscopic three-dimensional left Ventricular mapping system showed considerable changes in voltage potentials and mechanical activity detected in ischemic and infracted myocardial regions with mechanical dysfunction. This study examined the electromechanical characteristics in relation to regional wail motion assessed by echocardiography in patients with coronary artery disease. A 12-segment model of mapping (apical,mid, basal of septal, anterior, lateral, and inferior/posterior segments) was compared to echo wall motion score in 74 patients (836 segments). Unipolar voltage and local endocardial shortening signals were distinguished according to graded echo segmental rest scores (0 = normal, 1 = mild hypokinesis, 2 = moderate hypokinesis, 3 = severe hypokinesis, 4 = akinesis). Results show a significant difference in voltage potentials and shortening valuesin groups distinguished according to echocardiography motion score. The average voltage potentials and shortening values were highest in myocardial segments with normal or slightly reduced contractility and lowest in myocardial segments with moderate to severely impaired contractility scores (voltage: 12.3 +/- 5.0, 12.1 +/- 5.3, 10.7 +/- 5.4, 8.7 +/- 3.9, 7.1 +/- 3.0 mV, P = 0.0001; local shortening: 9.7 +/- 6.5, 8.4 +/- 5.9, 8.0 +/- 5.4, 5.6 +/- 6.3, 5.1 +/- 4.6%, P = 0.0001 in regions with segmental scores of 0, 1, 2, 3, 4 by echo, respectively). Using receiver-operating curve calculations,the area under the curve was 0.72 +/- 0.06 (voltage) and 0.67 +/- 0.05 (local shortening) without a significant difference between the two curves. The 90% thresholds for defining preserved vs. impaired contractility were 12.8 and 5.6 mV for voltage and 12.6% and 1.6% for local shortening. We conclude that electromechanical mapping correlates with regional changes in wall motion scores assessed by echo, showing a gradual proportional decrease in measured voltage and shortening signals in segments with impaired function. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 14:50:11