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Titolo:
The mammary myoepithelial cell - Cinderella or ugly sister?
Autore:
Lakhani, SR; OHare, MJ;
Indirizzi:
Royal Free & Univ Coll Med Sch, Dept Histopathol, Breast Mol Pathol Lab, London, England Royal Free & Univ Coll Med Sch London England thol Lab, London, England Royal Free & Univ Coll Med Sch, LICR UCL Breast Canc Lab, London, England Royal Free & Univ Coll Med Sch London England Canc Lab, London, England
Titolo Testata:
BREAST CANCER RESEARCH
fascicolo: 1, volume: 3, anno: 2001,
pagine: 1 - 4
SICI:
1465-542X(2001)3:1<1:TMMC-C>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
LUMINAL EPITHELIAL-CELLS; COMPARATIVE GENOMIC HYBRIDIZATION; BREAST-CANCER; IMMUNOMAGNETIC SEPARATION; MALIGNANT MYOEPITHELIOMA; GENETIC ALTERATIONS; BASEMENT-MEMBRANE; GLAND; DIFFERENTIATION; CARCINOMA;
Keywords:
breast; breast cancer; cell biology; myoepithelial; pathology;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Lakhani, SR Univ Coll London, Royal Free & Univ Coll Med Sch, Dept Histopathol, BreastMol Pathol Lab, Rockefeller Bldg,Univ St, London WC1E 6JJ, England Univ Coll London Rockefeller Bldg,Univ St London England WC1E 6JJ
Citazione:
S.R. Lakhani e M.J. O'Hare, "The mammary myoepithelial cell - Cinderella or ugly sister?", BREAST CA R, 3(1), 2001, pp. 1-4

Abstract

The breast myoepithelial cell is the Cinderella of mammary biology. Although its contribution to benign and some malignant pathologies is recognised,it has been largely neglected in molecular and biological studies. The reason for this has been the perception that its role in normal physiology is confined to lactation and the belief that most breast cancers arise from luminal epithelial cells. This review presents our perspective on its broaderbiological significance and its potential use as a model system for understanding breast carcinogenesis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 14:56:42