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Titolo:
Distribution and cardiovascular risk correlates of serum triglycerides in young adults from a biracial community - The Bogalusa Heart Study
Autore:
Frontini, MG; Srinivasan, SR; Elkasabany, A; Berenson, GS;
Indirizzi:
Tulane Univ, Sch Publ Hlth & Trop Med, Tulane Ctr Cardiovasc Hlth, Dept Epidemiol, New Orleans, LA 70112 USA Tulane Univ New Orleans LA USA 70112 Epidemiol, New Orleans, LA 70112 USA
Titolo Testata:
ATHEROSCLEROSIS
fascicolo: 1, volume: 155, anno: 2001,
pagine: 201 - 209
SICI:
0021-9150(200103)155:1<201:DACRCO>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; DENSITY-LIPOPROTEIN CHOLESTEROL; DEPENDENT DIABETES-MELLITUS; INSULIN-RESISTANCE; MYOCARDIAL-INFARCTION; PLASMA TRIGLYCERIDES; ADIPOSE-TISSUE; ENDOGENOUS HYPERTRIGLYCERIDEMIA; FACTOR-VII; MEN;
Keywords:
triglycerides; cardiovascular risk; young adults; white-black;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
56
Recensione:
Indirizzi per estratti:
Indirizzo: Berenson, GS Tulane Univ, Sch Publ Hlth & Trop Med, Tulane Ctr Cardiovasc Hlth, Dept Epidemiol, 21st Floor,1440 Canal St, New Orleans, LA 70112 USA Tulane Univ 21st Floor,1440 Canal St New Orleans LA USA 70112
Citazione:
M.G. Frontini et al., "Distribution and cardiovascular risk correlates of serum triglycerides in young adults from a biracial community - The Bogalusa Heart Study", ATHEROSCLER, 155(1), 2001, pp. 201-209

Abstract

Elevated serum triglyceride level is increasingly being recognized as an important indicator of cardiovascular risk. The distribution and correlates of serum triglycerides were examined in a biracial (black-white) community-based sample of 1342 young adults (30% black) aged 20-37 years. Triglyceride levels showed significant race (white > black) and sex (male > female) differences. Black females, despite their relatively increased body fatness, had lowest triglyceride levels. In terms of conjoint trait of dyslipidemia based on the National Cholesterol Education Program cutpoints, 9% of white males displayed high triglyceride (greater than or equal to 200 mg/dl) in combination with low high-density lipoprotein (HDL)-cholesterol (< 35 mg/dl). In comparison, none of the black females fell into this category. Serum triglycerides even at levels between 100 and 150 mg/dl were significantly adversely associated with risk variables of insulin resistance syndrome such as adiposity and visceral fatness measures, HDL-choleslerol, insulin, and systolic blood pressure, especially among whites. Visceral fatness as measured by waist circumference (except black males) and insulin were the major predictors of triglyceride levels. Overall, triglyceride levels above 150 mg/dl were associated with increased risk of hypertension (odds ratio (OR) = 1.8, 95% confidence interval (CI) = 1.8-3.0), type 2 diabetes (OR = 3.1, CI= 1.4-6.9), parental history of hypertension (OR = 1.3, CI = 1.0-1.8) and parental history of type 2 diabetes (OR = 1.7, CI = 1.2-2.3). Thus, serum triglyceride levels may be valuable in the assessment of cardiovascular riskduring young adulthood. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

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Documento generato il 23/01/20 alle ore 06:27:17