Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Decision analysis for the cost-effective management of recurrent colorectal cancer
Autore:
Park, KC; Schwimmer, J; Shepherd, JE; Phelps, ME; Czernin, JR; Schiepers, C; Gambhir, SS;
Indirizzi:
Univ Calif Los Angeles, Sch Med, Crump Inst Mol Imaging, Dept Mol & Med Pharmacol,Div Nucl Med, Los Angeles, CA 90095 USA Univ Calif Los Angeles LosAngeles CA USA 90095 Los Angeles, CA 90095 USA Univ Calif Los Angeles, Sch Med, Dept Biomath, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles, CA 90095 USA
Titolo Testata:
ANNALS OF SURGERY
fascicolo: 3, volume: 233, anno: 2001,
pagine: 310 - 319
SICI:
0003-4932(200103)233:3<310:DAFTCM>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION-TOMOGRAPHY; CARCINOEMBRYONIC ANTIGEN; HEPATIC RESECTION; FOLLOW-UP; COLON-CANCER; F-18 FLUORODEOXYGLUCOSE; LIVER METASTASES; FDG-PET; CARCINOMA; UTILITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Gambhir, SS Univ Calif Los Angeles, Sch Med, Crump Inst Mol Imaging, Dept Mol & Med Pharmacol,Div Nucl Med, B3-399A BRI,Box 951770,700 Westwood Plaza, Los Angeles, CA 90095 USA Univ Calif Los Angeles B3-399A BRI,Box 951770,700 Westwood Plaza Los Angeles CA USA 90095
Citazione:
K.C. Park et al., "Decision analysis for the cost-effective management of recurrent colorectal cancer", ANN SURG, 233(3), 2001, pp. 310-319

Abstract

Objective To determine whether the use of [18F]2-fluoro-2-deoxyglucose positron emission tomography (FDG PET) in addition to computed axial tomography (CT) is helpful in managing recurrent colorectal cancer (CRC). Summary Background Data There is no consensus on a management algorithm for CRC. However, when recurrence is suspected, CT is generally used for further evaluation and staging of disease. Methods The authors used decision trees based on theoretical models to assess the cost-effectiveness of a CT + FDG PET strategy for the diagnosis andmanagement of recurrent CRC compared with a CT-alone strategy. These theoretical models focus on patients with hepatic recurrence who are potentiallycurable through surgical hepatic resection. The population entering the decision trees consisted of patients with CRC who had undergone surgical resection of their primary CRG and who were suspected of having recurrence based on elevated revels of carcinoembryonic antigen. Results The CT + FDG PET strategy was found to be cost-effective for managing patients with elevated carcinoembryonic antigen levels who were candidates for hepatic resection. The CT + FDG PET strategy was higher in mean cost by $429 per patient but resulted in an increase in the mean life expectancy of 9.527 days per patient. Conclusions These results show, through rigorous decision tree analysis, the potential cost-effectiveness of FDG. PET in the management of recurrent CRC. The decision trees can be used to model various features of the management of recurrent CRC, including the cost-effectiveness of other newly emerging technologies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/07/20 alle ore 19:47:14