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Titolo:
Abdominal thrombotic and ischemic manifestations of the antiphospholipid antibody syndrome: CT findings in 42 patients
Autore:
Kaushik, S; Federle, MP; Schur, PH; Krishnan, M; Silverman, SG; Ros, PR;
Indirizzi:
Univ Pittsburgh, Med Ctr Presbyterian Hosp, Dept Radiol, Pittsburgh, PA 15213 USA Univ Pittsburgh Pittsburgh PA USA 15213 Radiol, Pittsburgh, PA 15213 USA Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Radiol, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 h Med, Dept Radiol, Boston, MA 02115 USA Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Med, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 Sch Med, Dept Med, Boston, MA 02115 USA
Titolo Testata:
RADIOLOGY
fascicolo: 3, volume: 218, anno: 2001,
pagine: 768 - 771
SICI:
0033-8419(200103)218:3<768:ATAIMO>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYSTEMIC LUPUS-ERYTHEMATOSUS; IMAGING FINDINGS; ANTICARDIOLIPIN ANTIBODIES; RENAL INFARCTION; COMPLICATIONS; HEMORRHAGE; PREVALENCE;
Keywords:
abdomen, CT; antiphospholipid syndrome; arteries, thrombosis; lupus erythematosus; veins, thrombosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Federle, MP Univ Pittsburgh, Med Ctr Presbyterian Hosp, Dept Radiol, 200 Lothrop St,Room 4660 CHP MT, Pittsburgh, PA 15213 USA Univ Pittsburgh 200 Lothrop St,Room 4660 CHP MT Pittsburgh PA USA 15213
Citazione:
S. Kaushik et al., "Abdominal thrombotic and ischemic manifestations of the antiphospholipid antibody syndrome: CT findings in 42 patients", RADIOLOGY, 218(3), 2001, pp. 768-771

Abstract

PURPOSE: To determine the abdominal computed tomographic (CT) findings in patients with antiphospholipid antibody syndrome (APS). MATERIALS AND METHODS: Retrospective review of medical records from two university medical centers from 1994 through 1997 revealed 215 patients who had a hypercoagulable state attributed to primary or secondary APS. Abdominal CT findings in these patients were reviewed for evidence of large-vessel occlusion or visceral ischemia. RESULTS: In 42 (19.5%) of 215 patients with APS (age range, 32-65 years; mean age, 42 years), abdominal thromboses or ischemic events were detected at CT. Twenty-two (52%) had major vascular thromboses, including those in the inferior vena cava (n = 10), portal and superior mesenteric veins (n = 7), splenic vein (n = 4), and aorta (n = 1). Thirty-six (86%) patients had abdominal visceral ischemia resulting in renal infarction (n = 22), bowel ischemia (n = 13), splenic infarction (n = 6), pancreatitis (n = 3), hepatic infarction (n = 1), and/or hepatic dysfunction with portal hypertension (n =1). In some patients, more than one abdominal organ and/or vessel was involved. CONCLUSION: Patients who have circulating antiphospholipid antibodies are at risk for major abdominal vascular thromboses and organ infarction. Radiologists must be familiar with this syndrome; they may be the first physicians to suggest the diagnosis on the basis of findings of unusual or recurrent sites of thrombosis, especially in young patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 19:16:23