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Titolo:
Hypervascular hepatocellular carcinoma: Detection with double arterial phase multi-detector row helical CT
Autore:
Murakami, T; Kim, T; Takamura, M; Hori, M; Takahashi, S; Federle, MP; Tsuda, K; Osuga, K; Kawata, S; Nakamura, H; Kudo, M;
Indirizzi:
Osaka Univ, Sch Med, Dept Radiol, Suita, Osaka 5650871, Japan Osaka Univ Suita Osaka Japan 5650871 Radiol, Suita, Osaka 5650871, Japan Univ Pittsburgh, Med Ctr, Dept Radiol, Pittsburgh, PA USA Univ PittsburghPittsburgh PA USA d Ctr, Dept Radiol, Pittsburgh, PA USA GE Yokohama Med Syst, Tokyo, Japan GE Yokohama Med Syst Tokyo JapanGE Yokohama Med Syst, Tokyo, Japan
Titolo Testata:
RADIOLOGY
fascicolo: 3, volume: 218, anno: 2001,
pagine: 763 - 767
SICI:
0033-8419(200103)218:3<763:HHCDWD>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
IODIZED OIL; SPIRAL CT; PORTOGRAPHY; LIVER;
Keywords:
computed tomography (CT), helical; computed tomography (CT), technology; liver, CT; liver neoplasms, diagnosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Murakami, T Osaka Univ, Sch Med, Dept Radiol, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan Osaka Univ 2-2 Yamadaoka Suita Osaka Japan 5650871 0871, Japan
Citazione:
T. Murakami et al., "Hypervascular hepatocellular carcinoma: Detection with double arterial phase multi-detector row helical CT", RADIOLOGY, 218(3), 2001, pp. 763-767

Abstract

PURPOSE: To assess whether double arterial phase imaging with multi-detector row helical computed tomography improves detection of hypervascular hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Fifty-one patients with 96 hypervascular HCCs underwent double arterial phase imaging of the entire liver. At measured delay after intravenous administration of 2 mL/kg of contrast medium at a rate of 5 mL/sec, the early and late arterial phase images were obtained serially during a single breath hold with interscan delay of 5.0 seconds. Detector row configuration of 2.5 x 4 mm, pitch of 6, and scanning time of 10.5 seconds for each phase were used. Forty 5-mm-thick reconstruction images were obtained for each phase. Each image set was interpreted separately by three observers, who were unaware of tumor burden in the liver, to detect hypervascular HCC. Sensitivity, positive predictive value, and area below the receiver operating characteristic curve (A(z)) for early and late arterial phasesseparately and together were calculated. RESULTS: Mean sensitivity and positive predictive value for hypervascular HCC were 54% and 85% for the early arterial phase, 78% and 83% for the latearterial phase, and 86% and 92% for the double arterial phase, respectively. Double arterial phase imaging showed significantly superior sensitivity compared with early or late arterial phase imaging alone for detecting HCC (P < .05). The mean A(z) value for double arterial phase was significantly higher than that for early or late arterial phase imaging alone (P < .05). Double arterial phase imaging showed the lowest number of false-positive lesions. CONCLUSION: Double arterial phase imaging is recommended to improve detection of hypervascular HCCs and reduce false-positive lesions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 23:14:36