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Titolo:
Multiple roles of Eph receptors and ephrins in neural development
Autore:
Wilkinson, DG;
Indirizzi:
Natl Inst Med Res, Div Dev Neurobiol, London NW7 1AA, England Natl Inst Med Res London England NW7 1AA robiol, London NW7 1AA, England
Titolo Testata:
NATURE REVIEWS NEUROSCIENCE
fascicolo: 3, volume: 2, anno: 2001,
pagine: 155 - 164
SICI:
1471-0048(200103)2:3<155:MROERA>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
GANGLION-CELL AXONS; TYROSINE KINASE RECEPTOR; TRANSMEMBRANE LIGANDS; NEURITE OUTGROWTH; XENOPUS-LAEVIS; VISUAL-SYSTEM; C-ELEGANS; IN-VITRO; CARDIOVASCULAR DEVELOPMENT; AUTOPHOSPHORYLATION SITE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
120
Recensione:
Indirizzi per estratti:
Indirizzo: Wilkinson, DG Natl Inst Med Res, Div Dev Neurobiol, Mill Hill, London NW7 1AA, England Natl Inst Med Res Mill Hill London England NW7 1AA England
Citazione:
D.G. Wilkinson, "Multiple roles of Eph receptors and ephrins in neural development", NAT REV NEU, 2(3), 2001, pp. 155-164

Abstract

The control of cell movement during development is essential for forming and stabilizing the spatial organization of tissues and cell types. During initial steps of tissue patterning, distinct regional domains or cell types arise at appropriate locations, and the movement of cells is constrained inorder to maintain spatial relationships during growth. In other situations, the guidance of migrating cells or neuronal growth cones to specific destinations underlies the establishment or remodelling of a pattern. Eph receptor tyrosine kinases and their ephrin ligands are key players in controlling these cell movements in many tissues and at multiple stages of patterning.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 00:57:20