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Titolo:
Lateralized normosmia in a patient with Kallmann's syndrome.
Autore:
Wustenberg, EG; Fleischer, A; Gerbert, B; Abolmaali, N; Huttenbrink, KB; Hummel, T;
Indirizzi:
Tech Univ Dresden, Univ HNO Klin, D-01307 Dresden, Germany Tech Univ Dresden Dresden Germany D-01307 Klin, D-01307 Dresden, Germany
Titolo Testata:
LARYNGO-RHINO-OTOLOGIE
fascicolo: 2, volume: 80, anno: 2001,
pagine: 85 - 89
SICI:
1615-0007(200102)80:2<85:LNIAPW>2.0.ZU;2-A
Fonte:
ISI
Lingua:
GER
Soggetto:
HYPOGONADOTROPIC HYPOGONADISM; OLFACTORY FUNCTION; ODOR IDENTIFICATION; ANOSMIC PATIENTS; GENE; ADHESION; DISCRIMINATION; HETEROGENEITY; THRESHOLDS; POTENTIALS;
Keywords:
olfaction; lateralisation; MRI; olfactory event-related potentials; "Sniffin' Sticks";
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Hummel, T Tech Univ Dresden, Univ HNO Klin, Fetscherstasse 74, D-01307 Dresden, Germany Tech Univ Dresden Fetscherstasse 74 Dresden Germany D-01307 any
Citazione:
E.G. Wustenberg et al., "Lateralized normosmia in a patient with Kallmann's syndrome.", LARY RH OTO, 80(2), 2001, pp. 85-89

Abstract

Background: Kallmann's syndrome (KS) was first mentioned in 1944 as an association of anosmia and hypogonadotropic hypogonadism. Causes are multiple genetic defects the most common of which is the x-linked KS appearing mostly in men. However, autosomal dominat and autosomal recessive forms have also been described. Patient: We present a case of KS with normosmia (male, 39years of age). All symptoms of hypogonadotropic hypogonadism were present. Results: Psychophysical olfactory testing revealed left-sided anosmia withright-sided normosmia which was confirmed by electrophysiological measuresof olfactory function. Magnetic resonance imaging indicated aplasia of theleft olfactory tract and bulb, whereas the right-sided structures appearedto be normal. Conclusions: As indicated in this case with lateralized anosmia and contralateral normosmia, overall olfactory function strongly depends on the "best" nostril. Therefore, in many clinical situations, lateralized olfactory testing appears to be extremely important.

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Documento generato il 05/04/20 alle ore 06:41:55