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Titolo:
Spontaneous acute tumor lysis syndrome with advanced gastric cancer
Autore:
Woo, IS; Kim, JS; Park, MJ; Lee, MS; Cheon, RW; Chang, HM; Ahn, JS; Lee, JA; Park, YI; Park, YS; Shim, JW; Yang, I;
Indirizzi:
Hallym Univ, Coll Med, Dept Internal Med, Seoul, South Korea Hallym Univ Seoul South Korea ed, Dept Internal Med, Seoul, South Korea Hallym Univ, Coll Med, Dept Pathol, Seoul, South Korea Hallym Univ SeoulSouth Korea Coll Med, Dept Pathol, Seoul, South Korea Hallym Univ, Coll Med, Dept Diagnost Radiol, Seoul, South Korea Hallym Univ Seoul South Korea Dept Diagnost Radiol, Seoul, South Korea
Titolo Testata:
JOURNAL OF KOREAN MEDICAL SCIENCE
fascicolo: 1, volume: 16, anno: 2001,
pagine: 115 - 118
SICI:
1011-8934(200102)16:1<115:SATLSW>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYNDROME COMPLICATING TREATMENT; CELL CARCINOMA; CHEMOTHERAPY;
Keywords:
tumor lysis syndrome; stomach neoplasms; solid tumor;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Cheon, RW Hallym Univ, Kangnam Sacred Heart Hosp, Dept Internal Med, Youndeungpo Gu,Seoul 150071, South Korea Hallym Univ Seoul South Korea 150071 Seoul 150071, South Korea
Citazione:
I.S. Woo et al., "Spontaneous acute tumor lysis syndrome with advanced gastric cancer", J KOR MED S, 16(1), 2001, pp. 115-118

Abstract

Acute tumor lysis syndrome (TLS) occurs frequently in hematologic malignancies such as high-grade lymphomas and acute leukemia, which are rapidly proliferating and chemosensitive tumors. It occurs rarely in solid tumors and has never been reported in gastric adenocarcinoma. Typical biochemical findings of acute tumor lysis syndrome are hyperuricemia, hyperkalemia, hyperphosphatemia and hypocalcemia in patients with a malignancy. Rapid changes ofthese electrolytes may cause cardiac arrhythmia, seizure, acute renal failure and sudden death. Therefore, as soon as it is detected, it should be taken care of immediately. Until now almost all cases of TLS associated with solid tumor have developed after cytoreductive therapy in chemosensitive tumors. We report here a case of spontaneous acute tumor lysis in a patient of advanced gastric cancer with hepatic metastases and multiple lymphadenopathy. The biochemical finding of TLS improved with the management and tumor burden also showed slight response to the one cycled combination chemotherapy but the patient died of progressive pneumonia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/10/20 alle ore 00:25:16