Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Immunohistochemical analysis of equine pulmonary granular cell tumours
Autore:
Kagawa, Y; Hirayama, K; Tagami, M; Tsunoda, N; Yoshino, T; Matsui, T; Furuoka, H; Taniyama, H;
Indirizzi:
Rakuno Gakuen Univ, Sch Vet Med, Dept Vet Pathol, Ebetsu, Hokkaido 0698501, Japan Rakuno Gakuen Univ Ebetsu Hokkaido Japan 0698501 Hokkaido 0698501, Japan Shadai Stall Stn, Muroran, Hokkaido 0501432, Japan Shadai Stall Stn Muroran Hokkaido Japan 0501432 , Hokkaido 0501432, Japan Obihiro Univ Agr & Vet Med, Dept Vet Pathol, Obihiro, Hokkaido 0800835, Japan Obihiro Univ Agr & Vet Med Obihiro Hokkaido Japan 0800835 0800835, Japan
Titolo Testata:
JOURNAL OF COMPARATIVE PATHOLOGY
fascicolo: 2-3, volume: 124, anno: 2001,
pagine: 122 - 127
SICI:
0021-9975(200102/04)124:2-3<122:IAOEPG>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
TUMORS; HORSE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Taniyama, H Rakuno Gakuen Univ, Sch Vet Med, Dept Vet Pathol, Bunkyodai Midorimachi 582-1, Ebetsu, Hokkaido 0698501, Japan Rakuno Gakuen Univ Bunkyodai Midorimachi 582-1 Ebetsu Hokkaido Japan 0698501
Citazione:
Y. Kagawa et al., "Immunohistochemical analysis of equine pulmonary granular cell tumours", J COMP PATH, 124(2-3), 2001, pp. 122-127

Abstract

Histopathological and immunohistochemical examinations were made on four female horses aged 9 12 years with pulmonary granular cell tumours (GCTs). The tumours, which were multiple, of varying size, firm and off-white ill colour, surrounded the bronchi and bronchioles. Metastatic lesions were not detected. The tumour cells had abundant eosinophilic cytoplasm filled with prominent coarse eosinophilic granules. Immunohistochemically, there tumour cells reacted uniformly with vimentin and S100 antibodies. Most were immunolabelled by antibodies against glial fibrillary acidic protein (GFAP), myelin basic protien (MBP) and protein gene product 9.5 (PGP9.5), and a few cells were positive with Leu7 antibody. However, the tumour cells did not react with antibodies against neurofilament protien (NF), cytokeratin (CK), chromogranin, alpha1 antichymotrypsin (AACT), myglobin, desmin, alpha -actin or alpha -smooth muscle actin (alpha -SMA). These immunohistochemical properties of tumour cells support the hypothesis that equine pulmonary GCTs are derived from Schwann cells of the peripheral nervous system in perbronchialand peribronchiolar tissues. GFAP, MBP, Leu7 and PGP9.5 antibodies should help to distinguish equine granular cell tumours from other tumours.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 19:17:04