Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Possible neurobiological mechanisms underlying faster onset of antidepressant action
Autore:
Blier, P;
Indirizzi:
Univ Florida, Inst Brain, Dept Psychiat, Gainesville, FL 32611 USA Univ Florida Gainesville FL USA 32611 Psychiat, Gainesville, FL 32611 USA
Titolo Testata:
JOURNAL OF CLINICAL PSYCHIATRY
, volume: 62, anno: 2001, supplemento:, 4
pagine: 7 - 11
SICI:
0160-6689(2001)62:<7:PNMUFO>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEROTONIN REUPTAKE INHIBITORS; PLACEBO-CONTROLLED TRIAL; POSTSYNAPTIC 5-HT1A RECEPTORS; ANTI-DEPRESSANT TREATMENT; MAJOR DEPRESSION; DOUBLE-BLIND; RAT-BRAIN; AMYGDALOID NEURONS; INDUCED REMISSION; FIRING ACTIVITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Blier, P Univ Florida, Inst Brain, Dept Psychiat, 100 Newell Dr,Suite L4-100, Gainesville, FL 32611 USA Univ Florida 100 Newell Dr,Suite L4-100 Gainesville FL USA 32611
Citazione:
P. Blier, "Possible neurobiological mechanisms underlying faster onset of antidepressant action", J CLIN PSY, 62, 2001, pp. 7-11

Abstract

All antidepressant drugs have a delayed onset of action. There is, however, evidence that some agents may attenuate depressive symptoms more rapidly than others. The present review examines the mechanisms by which selective serotonin reuptake inhibitors, the dual 5-HT norepinephrine reuptake inhibitor venlafaxine, and the alpha (2)-adrenoceptor antagonist mirtazapine alter 5-HT and/or norepinephrine neurotransmission. Particular attention is given to the time course with which these effects manifest themselves in relation to the possibility that these 3 types of drugs may act more rapidly, orexert a greater antidepressant action, than other agents. Based on the effects of antidepressant drugs presently available, strategies to accelerate or augment the antidepressant response are described, some of which have already been examined in patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 00:33:06