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Titolo:
Advances in functional neuroimaging methodology for the study of brain systems underlying human neuropsychological function and dysfunction
Autore:
Stern, E; Silbersweig, DA;
Indirizzi:
Cornell Univ, Weill Med Coll, Dept Psychiat, Funct Neuroimaging Lab, New York, NY 10021 USA Cornell Univ New York NY USA 10021 uroimaging Lab, New York, NY 10021 USA
Titolo Testata:
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY
fascicolo: 1, volume: 23, anno: 2001,
pagine: 3 - 18
SICI:
1380-3395(200102)23:1<3:AIFNMF>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION-TOMOGRAPHY; CEREBRAL BLOOD-FLOW; SURFACE-BASED ANALYSIS; SENSORY STIMULATION; CLINICAL-ASSESSMENT; ALZHEIMERS-DISEASE; MR SPECTROSCOPY; SINGLE SUBJECTS; ACOUSTIC NOISE; DATA SETS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
83
Recensione:
Indirizzi per estratti:
Indirizzo: Silbersweig, DA Cornell Univ, Weill Med Coll, Dept Psychiat, Funct Neuroimaging Lab, 1300 York Ave, New York, NY 10021 USA Cornell Univ 1300 York AveNew York NY USA 10021 10021 USA
Citazione:
E. Stern e D.A. Silbersweig, "Advances in functional neuroimaging methodology for the study of brain systems underlying human neuropsychological function and dysfunction", J CL EXP N, 23(1), 2001, pp. 3-18

Abstract

Functional neuroimaging allows the non-invasive identification of distributed patterns of human brain activity associated with perceptual, congnitive, emotional and behavioral processes, in health and disease. Work in this field is methodologically intensive, requiring an interdisciplinary team of scientists to develop and apply rapidly advancing techniques. Here we focusupon the principles and methods of functional imaging, from hypothesis generation and study design, to subject recruitment and clinical characterization, neuropsychological paradigm development, image acquisition, image processing and statistical analysis, and data interpretation. The strengths andlimitations of the various techniques are discussed, with an emphasis on positron emission tomography (PET) and functional magnetic resonance imaging(fMRI), which have proven to be powerful tools for human brain mapping. The integration of these techniques with electroencephalography (EEC) and magnetoencephalography (MEG), which provide greater temporal information, is outlined. An understanding of such methodological issues is a necessary prerequisite to the development of new imaging methods with improved capabilities, to the careful application of existing methods to neuropsychological problems, and to the critical examination of planned or published studies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 13:53:37