Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Reelin-immunoreactive neurons in the adult vertebrate pallium
Autore:
Perez-Garcia, CG; Gonzalez-Delgado, FJ; Suarez-Sola, ML; Castro-Fuentes, R; Martin-Trujillo, JM; Ferres-Torres, R; Meyer, G;
Indirizzi:
Univ La Laguna, Dept Anat, Tenerife 38071, Spain Univ La Laguna TenerifeSpain 38071 na, Dept Anat, Tenerife 38071, Spain Univ La Laguna, Dept Physiol, Tenerife 38071, Spain Univ La Laguna Tenerife Spain 38071 Dept Physiol, Tenerife 38071, Spain Univ La Laguna, Dept Cell Biol, Tenerife 38071, Spain Univ La Laguna Tenerife Spain 38071 ept Cell Biol, Tenerife 38071, Spain
Titolo Testata:
JOURNAL OF CHEMICAL NEUROANATOMY
fascicolo: 1, volume: 21, anno: 2001,
pagine: 41 - 51
SICI:
0891-0618(200101)21:1<41:RNITAV>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
MESSENGER-RNA EXPRESSION; CAJAL-RETZIUS CELLS; EMBRYONIC BRAIN-DEVELOPMENT; HUMAN ENTORHINAL CORTEX; HUMAN NEOCORTEX; HIPPOCAMPAL CONNECTIONS; ALZHEIMERS-DISEASE; VISUAL-CORTEX; VLDL RECEPTOR; GENE;
Keywords:
brain evolution; neocortex; molecular layer; interneurons; entorhinal cortex;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
57
Recensione:
Indirizzi per estratti:
Indirizzo: Meyer, G Univ La Laguna, Dept Anat, Tenerife 38071, Spain Univ La Laguna Tenerife Spain 38071 Anat, Tenerife 38071, Spain
Citazione:
C.G. Perez-Garcia et al., "Reelin-immunoreactive neurons in the adult vertebrate pallium", J CHEM NEUR, 21(1), 2001, pp. 41-51

Abstract

Reelin, an extracellular matrix protein, plays a crucial role in cortical development. By using Reelin-immunohistochemistry in different vertebrates (fish, amphibians, reptiles, and mammals: insectivores, odontocetes, rodents, carnivores and man) we show here that Reelin is also expressed by a variety of neurons in the adult pallium. In the everted telencephalon of the zebrafish, Reelin-positive neurons are widely distributed over the dorsal pallium. In land vertebrates, the most consistent and evolutionary conserved location of Reelin-expressing neurons is in the cell-sparse molecular layer associated with laminated cortical organization. We describe an additional heterogeneous population of Reelin-positive neurons outside the molecular layer, the location and distribution of which are more variable, and which may reflect major evolutionary changes in cortical architecture. In squamatereptiles, the Reelin-negative main cell layer is flanked by a superficial and a deep plexiform layer which both contain Reelin-expressing neurons. Inmammals, Reelin-positive interneurons are dispersed throughout layers II-VI; the human neocortex is particularly poor in Reelin-positive interneurons. Reelin is also expressed by large stellate and modified pyramidal neuronsin layer II of the mammalian entorhinal cortex, and in the superficial lateral cortex of lizards. Examination of this cell population (layer II Pre-a) in human brains of different age groups points to a decrease in Reelin-expression in the course of adult life. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 18:30:53