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Titolo:
Single-dose pharmacokinetics of levofloxacin during continuous veno-venoushaemofiltration in critically ill patients
Autore:
Traunmuller, F; Thalhammer-Scherrer, R; Locker, GJ; Losert, H; Schmid, R; Staudinger, T; Thalhammer, F;
Indirizzi:
Univ Vienna, Dept Internal Med 1, Div Infect Dis, A-1090 Vienna, Austria Univ Vienna Vienna Austria A-1090 Div Infect Dis, A-1090 Vienna, Austria Univ Vienna, Dept Lab Med, A-1090 Vienna, Austria Univ Vienna Vienna Austria A-1090 , Dept Lab Med, A-1090 Vienna, Austria Univ Vienna, Intens Care Unit, Dept Internal Med 1, A-1090 Vienna, AustriaUniv Vienna Vienna Austria A-1090 Internal Med 1, A-1090 Vienna, Austria Univ Vienna, Inst Virol, A-1090 Vienna, Austria Univ Vienna Vienna Austria A-1090 na, Inst Virol, A-1090 Vienna, Austria
Titolo Testata:
Journal of antimicrobial chemotherapy
fascicolo: 2, volume: 47, anno: 2001,
pagine: 229 - 231
Fonte:
ISI
Lingua:
ENG
Soggetto:
OFLOXACIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Thalhammer, F Univ Vienna, Dept Internal Med 1, Div Infect Dis, WaehringerGuertel 18-20, A-1090 Vienna, Austria Univ Vienna Waehringer Guertel 18-20Vienna Austria A-1090
Citazione:
F. Traunmuller et al., "Single-dose pharmacokinetics of levofloxacin during continuous veno-venoushaemofiltration in critically ill patients", J ANTIMICRO, 47(2), 2001, pp. 229-231

Abstract

The present study was performed to analyse the pharmacokinetics of levofloxacin during continuous veno-venous haemofiltration (CVVH) with a high-fluxpolyamide membrane. Twelve patients received 500 mg levofloxacin intravenously. The mean levofloxacin concentration peak was 1.9 +/- 1.0 mg/L. The elimination half-life, haemofiltration clearance and total removal were 8.3 +/- 2.6 h, 27.6 +/- 8.4 mg/Lmin and 56 +/- 19%, respectively. Further multiple-dose studies are required to enable dosage recommendations to be made for patients receiving venal replacement therapy with CVVH.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 18:51:52