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Titolo:
Developing AIDS vaccine trials educational programs in Uganda
Autore:
McGrath, JW; Mafigiri, D; Kamya, M; George, K; Senvewo, R; Svilar, G; Kabugo, M; Mugishi, E;
Indirizzi:
Case Western Reserve Univ, Dept Anthropol, Cleveland, OH 44106 USA Case Western Reserve Univ Cleveland OH USA 44106 Cleveland, OH 44106 USA MRC, Kampala, Uganda MRC Kampala UgandaMRC, Kampala, Uganda Makerere Univ, Kampala, Uganda Makerere Univ Kampala UgandaMakerere Univ, Kampala, Uganda Family Hlth Int, Res Triangle Pk, NC USA Family Hlth Int Res Triangle Pk NC USA Hlth Int, Res Triangle Pk, NC USA Ctr Treatment & Rehabil Torture Victims, Kampala, Uganda Ctr Treatment & Rehabil Torture Victims Kampala Uganda Kampala, Uganda Case Western Reserve Univ, Sch Med, Dept Epidemiol & Biostat, Cleveland, OH 44106 USA Case Western Reserve Univ Cleveland OH USA 44106 Cleveland, OH 44106 USA Natl Social Secur Fund, Kampala, Uganda Natl Social Secur Fund Kampala Uganda ocial Secur Fund, Kampala, Uganda Joint Clin Res Ctr, Kampala, Uganda Joint Clin Res Ctr Kampala UgandaJoint Clin Res Ctr, Kampala, Uganda
Titolo Testata:
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
fascicolo: 2, volume: 26, anno: 2001,
pagine: 176 - 181
SICI:
1525-4135(20010201)26:2<176:DAVTEP>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
EFFICACY TRIALS; HIV; RISK; MEN; ACCEPTABILITY; WILLINGNESS; PARTICIPATE; GAY;
Keywords:
HIV vaccines; Uganda; informed consent; clinical trials;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: McGrath, JW Case Western Reserve Univ, Dept Anthropol, 10900 Euclid Ave, Cleveland, OH44106 USA Case Western Reserve Univ 10900 Euclid Ave Cleveland OH USA 44106
Citazione:
J.W. McGrath et al., "Developing AIDS vaccine trials educational programs in Uganda", J ACQ IMM D, 26(2), 2001, pp. 176-181

Abstract

In preparation for HIV vaccine trials, data on a cohort's knowledge about vaccines and vaccine studies are required so as to tailor educational materials to adequately meet local needs. Interviews (n = 1,182) conducted as part of a 3-year prospective study of Ugandan military men aged 18 to 30 years determined what information, in addition to standard trials information, would be required to ensure comprehension of trial procedures. The interviews highlighted four points: (1) the cohort has a lot of knowledge about vaccines but conflates whether vaccines cure or prevent disease; (2) there is a general lack of knowledge about clinical trials procedures; (3) the desire to be protected from HIV/AIDS is a common reason for being willing to participate in a hypothetical vaccine trial; and (4) concern about side effects is a common reason for being unwilling to participate in a trial. These four points guided the focus of the vaccine trials education, which used locally appropriate analogies to introduce complex unfamiliar concepts such asplacebos and blinding. This case study highlights the value of incorporating baseline interviews to assess the educational needs of study populations.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 12:27:28