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Titolo:
Giant negative T waves during interferon therapy in a patient with chronichepatitis C
Autore:
Fujiwara, T; Kiura, K; Ochi, K; Matsubara, H; Yamanari, H; Shimomura, H; Harada, M;
Indirizzi:
Okayama Univ, Sch Med, Dept Med 2, Okayama 7008558, Japan Okayama Univ Okayama Japan 7008558 d, Dept Med 2, Okayama 7008558, Japan
Titolo Testata:
INTERNAL MEDICINE
fascicolo: 2, volume: 40, anno: 2001,
pagine: 105 - 109
SICI:
0918-2918(200102)40:2<105:GNTWDI>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
VIRUS-INFECTION; HYPERTROPHIC CARDIOMYOPATHY; DILATED CARDIOMYOPATHY; MULTICENTER; HEART; RNA;
Keywords:
interferon-alpha; giant negative T waves; hypertension;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Kiura, K Okayama Univ, Sch Med, Dept Med 2, 2-5-1 Shikata cho, Okayama 7008558, Japan Okayama Univ 2-5-1 Shikata cho Okayama Japan 7008558 8558, Japan
Citazione:
T. Fujiwara et al., "Giant negative T waves during interferon therapy in a patient with chronichepatitis C", INTERN MED, 40(2), 2001, pp. 105-109

Abstract

Interferon-alpha (IFN-alpha) has been widely used for treatment of chronichepatitis C in Japan. In general, cardiovascular adverse reactions are rare in association with IFN-alpha therapy. Here, a 64-year-old man with chronic active hepatitis C complained of fatigue, palpitation and depression, and developed atrial fibrillation with prominent negative T waves during IFN-alpha therapy, Echocardiogram showed septal and apical hypertrophy, Three days after discontinuation of IFN-alpha, subjective symptoms and atrial fibrillation subsided. It is unclear whether or not IFN-alpha induced the giantnegative T waves with apical hypertrophy, We might observe the developing course of hepatitis C virus (HCV) related myocardial hypertrophy by chance. Cardiovascular toxicity should be carefully monitored during IFN-alpha therapy even in patients with minor cardiac disease, such as premature ventricular contracture (PVC) and mild hypertension.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 09:28:59