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Titolo: Antidepressants in clinical practice: Limitations of assessment methods and drug response
Autore: Kennedy, SH; Eisfeld, BS; Meyer, JH; Bagby, RM;
- Indirizzi:
- Univ Toronto, Ctr Addict & Mental Hlth, Toronto, ON M5T 1RB, Canada Univ Toronto Toronto ON Canada M5T 1RB Hlth, Toronto, ON M5T 1RB, Canada
- Titolo Testata:
- HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
fascicolo: 1,
volume: 16,
anno: 2001,
pagine: 105 - 114
- SICI:
- 0885-6222(200101)16:1<105:AICPLO>2.0.ZU;2-I
- Fonte:
- ISI
- Lingua:
- ENG
- Soggetto:
- ATYPICAL DEPRESSION; MAJOR DEPRESSION; DOUBLE-BLIND; EFFICACY; OUTPATIENTS; VENLAFAXINE; PHENELZINE; IMIPRAMINE; SETOPERONE; PAROXETINE;
- Keywords:
- antidepressants; efficacy; diagnostic heterogeneity functional brain imaging; Major Depressive Disorder;
- Tipo documento:
- Article
- Natura:
- Periodico
- Settore Disciplinare:
- Life Sciences
- Citazioni:
- 48
- Recensione:
- Indirizzi per estratti:
- Indirizzo: Kennedy, SH Univ Toronto, Ctr Addict & Mental Hlth, 250 Coll St, Toronto, ON M5T 1RB, Canada Univ Toronto 250 Coll St Toronto ON Canada M5T 1RB 1RB, Canada
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- Citazione:
- S.H. Kennedy et al., "Antidepressants in clinical practice: Limitations of assessment methods and drug response", HUM PSYCHOP, 16(1), 2001, pp. 105-114
Abstract
There is a recognized gap between knowledge derived from 'efficacy' data -based on usually brief randomized controlled trials and findings in natural practice 'effectiveness' studies. In considering the limitations of current antidepressants in clinical practice, we have selected three clinically important issues to examine in a natural practice data base that has been in existence for several years. These relate to: (I) Diagnostic heterogeneity and potential advances using functional brain imaging; (2) Variability ofoutcome measures during treatment and (3) Time to response and prediction of outcome. Copyright (C) 2001 John Wiley & Sons, Ltd.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/21 alle ore 20:16:34