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Titolo:
Assessment of the effect of revascularization early after CABG using EGG-gated perfusion single-photon emission tomography
Autore:
Kubo, S; Tadamura, E; Kudoh, T; Inubushi, M; Ikeda, T; Koshiji, T; Nishimura, K; Komeda, M; Tamaki, N; Konishi, J;
Indirizzi:
Kyoto Univ, Grad Sch Med, Dept Nucl Med & Diagnost Imaging, Sakyo Ku, Kyoto 6068507, Japan Kyoto Univ Kyoto Japan 6068507 t Imaging, Sakyo Ku, Kyoto 6068507, Japan Kyoto Univ, Fac Med, Dept Cardiovasc Surg, Kyoto 606, Japan Kyoto Univ Kyoto Japan 606 c Med, Dept Cardiovasc Surg, Kyoto 606, Japan Hokkaido Univ, Sch Med, Dept Nucl Med, Sapporo, Hokkaido 060, Japan Hokkaido Univ Sapporo Hokkaido Japan 060 ed, Sapporo, Hokkaido 060, Japan
Titolo Testata:
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
fascicolo: 2, volume: 28, anno: 2001,
pagine: 230 - 239
SICI:
0340-6997(200102)28:2<230:AOTEOR>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR FUNCTION; CORONARY-ARTERY DISEASE; INTERNAL MAMMARY ARTERY; REGIONAL WALL-MOTION; TRANSIENT ISCHEMIC DILATION; MYOCARDIAL PERFUSION; EJECTION FRACTION; TC-99M SESTAMIBI; TL-201 SCINTIGRAPHY; BYPASS-SURGERY;
Keywords:
coronary artery bypass graft surgery; single-photon emission tomography; arterial graft; transient ischaemic dilatation ratio;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Kubo, S Kyoto Univ, Grad Sch Med, Dept Nucl Med & Diagnost Imaging, Sakyo Ku, 54 Shogoin Kawahara, Kyoto 6068507, Japan Kyoto Univ 54 Shogoin Kawahara Kyoto Japan 6068507 6068507, Japan
Citazione:
S. Kubo et al., "Assessment of the effect of revascularization early after CABG using EGG-gated perfusion single-photon emission tomography", EUR J NUCL, 28(2), 2001, pp. 230-239

Abstract

When an arterial graft is used, reversible per fusion defects on single-photon emission tomography (SPET) perfusion images are occasionally observed early after coronary artery bypass graft surgery (CABG), owing to the restricted flow capacity. The purpose of this study was to determine whether thefunctional information obtained with electrocardiography (ECG)-gated perfusion SPET could be helpful in evaluating the effect of revascularization early after CABG. Twenty-three patients (18 men and 5 women, mean age 65+/-9 years) underwent stress/re-injection thallium-201 EGG-gated SPET before and4 weeks after CABG (13 with exercise and 10 with dipyridamole). Patency ofall grafts was confirmed by coronary angiography 1 month after CABG. Cardiac functional data including the left ventricular ejection fraction (LVEF) and the transient ischaemic dilatation (TID) ratio were analysed using a commercially available automated program. The conventional stress and re-injection tomograms were interpreted by means of a five-point scoring system ina nine-segment model. Stress-induced reversible (201)T1 perfusion defects were present in 64% of the myocardial segments bypassed by patent arterial,grafts, in contrast to 42% of the myocardial segments bypassed by patent venous grafts (chi (2)=7.8, P=0.005). Of the 23 patients, 12 showed improvement in summed ischaemic scores (group 1), while if had no change or deterioration (group 2), although all grafts were patent on postoperative catheterization. The TID ratio improved in both group 1 and group 2 before and afterCABG (1.14+/-0.13 vs 0.99+/-0.07, P=0.001 and 1.09+/-0.07 vs 0.94+/-0.05, P=0.002, respectively). However, LVEF did not significantly improve in group 1 or group 2 after CABG (42.5%+/-9.9% vs 47.5%+/-11.8%, and 52.1%+/-7.5% vs 53.1%+/-5.9%, respectively). Perfusion imaging or LVEF assessment is of Limited value early after CABG. The TID ratio obtained with EGG-gated perfusion SPET may be a useful marker to evaluate the effect of revascularization early after surgery.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 13:20:54