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Titolo:
Gabapentin in painful HIV-related neuropathy: a report of 19 patients, preliminary observations
Autore:
La Spina, I; Porazzi, D; Maggiolo, F; Bottura, P; Suter, F;
Indirizzi:
Osped Civile, Dept Neurol, I-21052 Busto Arsizio, Italy Osped Civile Busto Arsizio Italy I-21052 l, I-21052 Busto Arsizio, Italy Civil Hosp, Dept Infect Dis, I-21052 Busto Arsizio, Italy Civil Hosp Busto Arsizio Italy I-21052 Dis, I-21052 Busto Arsizio, Italy
Titolo Testata:
EUROPEAN JOURNAL OF NEUROLOGY
fascicolo: 1, volume: 8, anno: 2001,
pagine: 71 - 75
SICI:
1351-5101(200101)8:1<71:GIPHNA>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
RANDOMIZED CONTROLLED TRIAL; IMMUNODEFICIENCY-VIRUS INFECTION; PERIPHERAL NEUROPATHY; SENSORY NEUROPATHY; AMITRIPTYLINE; AIDS; DEMENTIA; COHORT;
Keywords:
Gabapentin; HIV; peripheral neuropathy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: La Spina, I Osped Civile, Dept Neurol, Piazzale Solaro 3, I-21052 Busto Arsizio, Italy Osped Civile Piazzale Solaro 3 Busto Arsizio Italy I-21052 ly
Citazione:
I. La Spina et al., "Gabapentin in painful HIV-related neuropathy: a report of 19 patients, preliminary observations", EUR J NEUR, 8(1), 2001, pp. 71-75

Abstract

The objective of this study was to assess the efficacy and safety of Gabapentin as the sole analgesic in patients with HIV-related painful neuropathy. Nineteen patients with HIV-related painful neuropathy were administered Gabapentin. Efficacy was evaluated with two 100-mm Visual Analogue Scales (VAS) (0: no symptom I 100: worst symptom), rating pain and interference of pain with sleep, performed at baseline and monthly intervals. Main Pain VAS score decreased from a baseline of 55.7 +/- 19.1 mm to a final 14.7 +/- 18.6 mm (ANOVA P = 0.0001) and mean Sleep Interference VAS score decreased From a baseline of 60.4 +/- 31.9 mm to a final 15.5 +/- 27.7 mm (ANOVA P = 0.0001). Gabapentin provided significant pain relief in our patients with HIV-associated painful sensory neuropathy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 07:31:10