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Titolo:
Alcohol consumption in relation to 20-year COPD mortality and pulmonary function in middle-aged men from three European countries
Autore:
Tabak, C; Smith, HA; Rasanen, L; Fidanza, F; Menotti, A; Nissinen, A; Feskens, EJM; Heederik, D; Kromhout, D;
Indirizzi:
Natl Inst Publ Hlth & Environm, Dept Chron Dis Epidemiol, NL-3720 BA Bilthoven, Netherlands Natl Inst Publ Hlth & Environm Bilthoven Netherlands NL-3720 BA herlands Univ Utrecht, Inst Risk Assessment Sci, Div Environm & Occupat Hlth, NL-3508 TC Utrecht, Netherlands Univ Utrecht Utrecht Netherlands NL-3508 TC 3508 TC Utrecht, Netherlands Erasmus Univ, Netherlands Inst Hlth Sci, NL-3000 DR Rotterdam, NetherlandsErasmus Univ Rotterdam Netherlands NL-3000 DR DR Rotterdam, Netherlands Univ Helsinki, Div Nutr, FIN-00014 Helsinki, Finland Univ Helsinki Helsinki Finland FIN-00014 tr, FIN-00014 Helsinki, Finland Univ Perugia, Dept Internal Med & Endocrinol & Metab Sci, Nutr Sect, I-06100 Perugia, Italy Univ Perugia Perugia Italy I-06100 ci, Nutr Sect, I-06100 Perugia, Italy Univ Minnesota, Sch Publ Hlth, Div Epidemiol, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 demiol, Minneapolis, MN 55455 USA Univ Kuopio, Dept Publ Hlth & Gen Practice, FIN-70211 Kuopio, Finland UnivKuopio Kuopio Finland FIN-70211 Practice, FIN-70211 Kuopio, Finland Kuopio Univ Hosp, Dept Neurol, SF-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland SF-70210 eurol, SF-70210 Kuopio, Finland Natl Inst Publ Hlth & Environm, Div Publ Hlth Res, NL-3720 BA Bilthoven, Netherlands Natl Inst Publ Hlth & Environm Bilthoven Netherlands NL-3720 BA herlands
Titolo Testata:
EPIDEMIOLOGY
fascicolo: 2, volume: 12, anno: 2001,
pagine: 239 - 245
SICI:
1044-3983(200103)12:2<239:ACIRT2>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-DISEASE; EMPHYSEMA; ADULTS; WOMEN; RISK;
Keywords:
alcohol consumption; chronic obstructive pulmonary disease mortality; pulmonary function; gender; international comparisons;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Tabak, C Natl Inst Publ Hlth & Environm, Dept Chron Dis Epidemiol, POB 1, NL-3720 BA Bilthoven, Netherlands Natl Inst Publ Hlth & Environm POB 1 Bilthoven Netherlands NL-3720 BA
Citazione:
C. Tabak et al., "Alcohol consumption in relation to 20-year COPD mortality and pulmonary function in middle-aged men from three European countries", EPIDEMIOLOG, 12(2), 2001, pp. 239-245

Abstract

Alcohol consumption shows a U-shaped relation with all-cause and cardiovascular mortality. To determine whether a similar relation exists between alcohol and chronic obstructive pulmonary disease mortality, we analyzed data on alcohol consumption in 1970 and 20-year mortality from chronic obstructive pulmonary disease among 2,953 middle-aged men from Finland, Italy, and the Netherlands. We also studied alcohol consumption in relation to pulmonary function (FEV1 or FEV0.75) at baseline. We used regression models adjusted for age, height (for pulmonary function only), body mass index, smoking habits, energy intake, and country. A smoothed spline-plot showed a U-shapedrelation between alcohol and chronic obstructive pulmonary disease mortality. Compared with non-drinkers and occasional drinkers, the relative risk of chronic obstructive pulmonary disease mortality was 0.60 (95% CI = 0.33-1.09) in light drinkers (>1 drink per week, less than or equal to3 drinks per day) and 1.25 (95% CI = 0.47-3.31) in moderate-to-heavy drinkers. Pulmonary function was lower in nondrinkers compared with occasional and light drinkers in Finland (75 mi, 95% CI = -2 to 151) and the Netherlands (93 ml, 95% CI = 0-186) and lower in very heavy (>12 drinks per day) compared with moderate-to-heavy drinkers in Italy (99 mi, 95% CI = 9-189). In conclusion, we observed a U-shaped curve between alcohol consumption and 20-year chronicobstructive pulmonary disease mortality in middle aged men that was supported by cross-sectional data on alcohol and pulmonary function.

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Documento generato il 25/09/20 alle ore 22:51:58