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Titolo:
High-throughput high-performance liquid chromatography/mass spectrometry for modern drug discovery
Autore:
Kyranos, JN; Cai, H; Wei, D; Goetzinger, WK;
Indirizzi:
Arqule Inc, Woburn, MA 01801 USA Arqule Inc Woburn MA USA 01801Arqule Inc, Woburn, MA 01801 USA
Titolo Testata:
CURRENT OPINION IN BIOTECHNOLOGY
fascicolo: 1, volume: 12, anno: 2001,
pagine: 105 - 111
SICI:
0958-1669(200102)12:1<105:HHLCSF>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
TANDEM MASS-SPECTROMETRY; SOLID-PHASE EXTRACTION; SUPERCRITICAL-FLUID CHROMATOGRAPHY; 96-WELL PLATE FORMAT; COMBINATORIAL LIBRARIES; SAMPLE PREPARATION; HUMAN PLASMA; HUMAN SERUM; HUMAN URINE; QUANTITATIVE-DETERMINATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
56
Recensione:
Indirizzi per estratti:
Indirizzo: Kyranos, JN Arqule Inc, 19 Presidential Way, Woburn, MA 01801 USA Arqule Inc 19 Presidential Way Woburn MA USA 01801 A 01801 USA
Citazione:
J.N. Kyranos et al., "High-throughput high-performance liquid chromatography/mass spectrometry for modern drug discovery", CURR OPIN B, 12(1), 2001, pp. 105-111

Abstract

High-throughput high-performance liquid chromatography/mass spectrometry can be used in the analysis of high-throughput organic synthesis products, bioanalytical target analysis for preclinical and clinical studies, and early absorption, distribution, metabolism and excretion (ADME) screening. New techniques are emerging, including system automation, faster analysis, programmed multiple extraction and analysis columns, multiple electrospray ionization channels, and automated 96-well sample preparation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 16:49:00