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Titolo:
Contrast-enhanced subtraction harmonic sonography for evaluating treatmentresponse in patients with hepatocellular carcinoma
Autore:
Ding, H; Kudo, M; Onda, H; Suetomi, Y; Minami, Y; Maekawa, K;
Indirizzi:
Kinki Univ, Sch Med, Dept Gastroenterol & Hepatol, Osaka 5898511, Japan Kinki Univ Osaka Japan 5898511 roenterol & Hepatol, Osaka 5898511, Japan Kinki Univ, Sch Med, Sect Abdominal Ultrasound, Osaka 5898511, Japan KinkiUniv Osaka Japan 5898511 bdominal Ultrasound, Osaka 5898511, Japan
Titolo Testata:
AMERICAN JOURNAL OF ROENTGENOLOGY
fascicolo: 3, volume: 176, anno: 2001,
pagine: 661 - 666
SICI:
0361-803X(200103)176:3<661:CSHSFE>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERCUTANEOUS ETHANOL INJECTION; TRANSCATHETER ARTERIAL EMBOLIZATION; COLOR DOPPLER US; CHEMOEMBOLIZATION THERAPY; HEPATIC METASTASES; AGENT; ULTRASOUND; ABLATION; LIVER; COAGULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Ding, H Kinki Univ, Sch Med, Dept Gastroenterol & Hepatol, 377-2, Osaka 5898511, Japan Kinki Univ 377-2 Osaka Japan 5898511 377-2, Osaka 5898511, Japan
Citazione:
H. Ding et al., "Contrast-enhanced subtraction harmonic sonography for evaluating treatmentresponse in patients with hepatocellular carcinoma", AM J ROENTG, 176(3), 2001, pp. 661-666

Abstract

OBJECTIVE. Our objective was to assess the usefulness of contrast-enhancedsubtraction harmonic sonography in evaluating the treatment response of patients with hepatocellular carcinoma. SUBJECTS AND METHODS. Thirty-two hepatocellular carcinoma lesions in 26 patients (age range. 44x85 years; mean age, 66 years) were examined with Levovist-enhanced intermittent harmonic imaging before and after therapy. A Toshiba Powervision 8000 was used. A subtraction image was obtained by digitally subtracting the last-frame harmonic image from the first-frame image when multishot mode was preset. Results of contrast-enhanced CT were compared with the results of subtraction harmonic imaging. RESULTS. Before therapy. an enhancement pattern of tumor vascularity was seen for 93.8% (30/32) of hepatocellular carcinoma nodules on subtraction harmonic imaging. After therapy, subtraction harmonic imaging showed 46.7% (14/30) enhancement (incomplete tumor necrosis) and 53.3% (16/30) no enhancement (complete tumor necrosis). When dynamic CT was the gold standard, the sensitivity, specificity, and accuracy of subtraction harmonic imaging were 93.3%, 100%, and 96.7%, respectively. Intratumoral flow signals in hepatocellular carcinoma after therapy on harmonic imaging were used as a guide to target additional percutaneous therapy. CONCLUSION. Digital subtraction contrast-enhanced harmonic imaging can depict tumor vascularity in hepatocellular carcinoma after therapy sensitivelyand accurately. Because it is easy to perform and provides real-time needle insertion guidance, it may be preferable to perform after localized therapy to monitor treatment response, which will reduce unnecessary CT scanning.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 11:20:36