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Titolo:
Innovative technologies for the diagnosis of alcohol abuse and monitoring abstinence
Autore:
Bean, P; Harasymiw, J; Peterson, CM; Javors, M;
Indirizzi:
Millennium Strategies, Madison, WI 53717 USA Millennium Strategies Madison WI USA 53717 ategies, Madison, WI 53717 USA Wisconsin & Rogers Mem Hosp, Oconomowoc, WI USA Wisconsin & Rogers Mem Hosp Oconomowoc WI USA m Hosp, Oconomowoc, WI USA Alcohol Detect Serv, Brookfield, WI USA Alcohol Detect Serv Brookfield WIUSA ol Detect Serv, Brookfield, WI USA Natl Lung Blood Inst, Div Blood Dis & Resources, Bethesda, MD USA Natl Lung Blood Inst Bethesda MD USA d Dis & Resources, Bethesda, MD USA Univ Texas, Hlth Sci Ctr, Dept Psychiat, San Antonio, TX 78284 USA Univ Texas San Antonio TX USA 78284 t Psychiat, San Antonio, TX 78284 USA
Titolo Testata:
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
fascicolo: 2, volume: 25, anno: 2001,
pagine: 309 - 316
SICI:
0145-6008(200102)25:2<309:ITFTDO>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARBOHYDRATE-DEFICIENT TRANSFERRIN; BLOOD-ASSOCIATED ACETALDEHYDE; GAMMA-GLUTAMYL-TRANSFERASE; HEMOGLOBIN-ASSOCIATED ACETALDEHYDE; LIQUID-CHROMATOGRAPHY; SERUM TRANSFERRIN; LIVER-DISEASE; CONSUMPTION; MARKER; HEAVY;
Keywords:
alcohol abuse; abstinence; biomarkers; carbohydrate-deficient transferrin; early detection of alcohol consumption; whole blood associated acetaldehyde;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
51
Recensione:
Indirizzi per estratti:
Indirizzo: Bean, P Millennium Strategies, 418 N Westfield Rd, Madison, WI 53717 USA Millennium Strategies 418 N Westfield Rd Madison WI USA 53717 USA
Citazione:
P. Bean et al., "Innovative technologies for the diagnosis of alcohol abuse and monitoring abstinence", ALC CLIN EX, 25(2), 2001, pp. 309-316

Abstract

This article summarizes the proceedings of a workshop presented at the 2000 RSA Meeting in Denver, Colorado. The aim of this workshop was to discuss the basic methodologies, diagnostic performance, and clinical utility of three technologies: carbohydrate-deficient transferrin, the "Early Detection of Alcohol Consumption" score, and whole blood associated acetaldehyde. Each method adopts a different strategy to identify heavy alcohol consumption and offers a unique approach to determine alcohol abstinence and relapses. Appropriate application of these technologies can lead to early intervention for alcohol problems before significant tissue damage occurs. To date these methodologies have yet to be formally contrasted and compared. Sensitivity, specificity, predictive value, availability, ease of use, and interpretation of tests results are important aspects to consider when selecting themost appropriate and cost-effective system. Critical evaluation of these methodologies can enable research and clinical laboratories to choose the system that best meets their particular needs in terms of assay feasibility, budget, and goals.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 15:56:02