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Titolo:
Pharmacogenomics of psychiatric disorders
Autore:
Pickar, D; Rubinow, K;
Indirizzi:
Comprehens NeuroSci Inc, Chevy Chase, MD 20815 USA Comprehens NeuroSci Inc Chevy Chase MD USA 20815 hevy Chase, MD 20815 USA
Titolo Testata:
TRENDS IN PHARMACOLOGICAL SCIENCES
fascicolo: 2, volume: 22, anno: 2001,
pagine: 75 - 83
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLOZAPINE-INDUCED AGRANULOCYTOSIS; RECEPTOR GENE POLYMORPHISMS; SEROTONIN TRANSPORTER GENE; APOLIPOPROTEIN-E GENOTYPE; ALZHEIMERS-DISEASE; ALLELIC VARIATION; 5-HT2A RECEPTOR; SCHIZOPHRENIC-PATIENTS; CLINICAL-RESPONSE; TACRINE THERAPY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
80
Recensione:
Indirizzi per estratti:
Indirizzo: Pickar, D Comprehens NeuroSci Inc, 4701 Willard Ave,Suite 105, Chevy Chase, MD 20815USA Comprehens NeuroSci Inc 4701 Willard Ave,Suite 105 Chevy Chase MD USA 20815
Citazione:
D. Pickar e K. Rubinow, "Pharmacogenomics of psychiatric disorders", TRENDS PHAR, 22(2), 2001, pp. 75-83

Abstract

Pharmacogenomics, the utilization of genetic information to predict outcome of drug treatment (therapeutic and side-effects), holds great promise forclinical medicine. The pharmacotherapy of psychiatric disorders exhibits wide variability in therapeutic response with little scientific guidance fortreatment on a patient-by-patient basis. The emerging field of pharmacogenomics holds great potential for refining and optimizing psychopharmacology. Key components for future development of the pharmacogenomics of psychiatric disorders include understanding the mechanism of drug action, identification of candidate genes and their variants, and weil-conducted clinical trials. In this article, data from recent studies are examined with particularemphasis on methodological requirements and direction for future research.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 09:38:27