Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The dopamine receptor DRD4 gene: are duplications distracting?
Autore:
Todd, RD; OMalley, KL;
Indirizzi:
Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA WashingtonUniv St Louis MO USA 63110 pt Psychiat, St Louis, MO 63110 USA Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA Washington Univ St Louis MO USA 63110 Dept Genet, St Louis, MO 63110 USA Washington Univ, Sch Med, Dept Anat & Neurobiol, St Louis, MO 63110 USA Washington Univ St Louis MO USA 63110 & Neurobiol, St Louis, MO 63110 USA
Titolo Testata:
TRENDS IN PHARMACOLOGICAL SCIENCES
fascicolo: 2, volume: 22, anno: 2001,
pagine: 55 - 56
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLONING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Todd, RD Washington Univ, Sch Med, Dept Psychiat, Campus Box 8134,660 S Euclid Ave,St Louis, MO 63110 USA Washington Univ Campus Box 8134,660 S Euclid Ave St Louis MO USA 63110
Citazione:
R.D. Todd e K.L. O'Malley, "The dopamine receptor DRD4 gene: are duplications distracting?", TRENDS PHAR, 22(2), 2001, pp. 55-56

Abstract

The dopamine D4 receptor DRD4 gene has been implicated in psychotic, mood,addictive, personality, movement and behavioral disorders [e.g. attention deficit hyperactivity disorder (ADHD)]. Now, there is convincing evidence to support the genetic association of DRD4 polymorphisms with ADHD. The particular polymorphism, a 5' 120-bp duplication. might be functionally active. These findings suggest that manipulation of the DRD4 gene pathway could offer more selective pharmacological approaches to the treatment of ADHD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 13:35:03