Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Application of an adapted international prognostic index for aggressive non-Hodgkin's lymphomas: Good discrimination and lower survival rates in Rio de Janeiro, Brazil
Autore:
Biasoli, I; Morais, JC; De Jesus, PS; Pulcheri, W; Nucci, M; Spector, N;
Indirizzi:
Univ Fed Rio de Janeiro, Hosp Univ Clementino Fraga Filho, Serv Hematol, BR-21941590 Ilha Do Fundao, Brazil Univ Fed Rio de Janeiro Ilha Do Fundao Brazil BR-21941590 BCndao, Brazil
Titolo Testata:
ONCOLOGY REPORTS
fascicolo: 2, volume: 8, anno: 2001,
pagine: 441 - 444
SICI:
1021-335X(200103/04)8:2<441:AOAAIP>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
LARGE-CELL LYMPHOMA; ELDERLY PATIENTS; CLASSIFICATION; DEHYDROGENASE; MODEL;
Keywords:
lymphoma; prognosis; chemotherapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Spector, N Univ Fed Rio de Janeiro, Hosp Univ Clementino Fraga Filho, ServHematol, Av Brigadeiro Trompowski S-N, BR-21941590 Ilha Do Fundao, Brazil Univ Fed Rio de Janeiro Av Brigadeiro Trompowski S-N Ilha Do Fundao BrazilBR-21941590 BC
Citazione:
I. Biasoli et al., "Application of an adapted international prognostic index for aggressive non-Hodgkin's lymphomas: Good discrimination and lower survival rates in Rio de Janeiro, Brazil", ONCOL REP, 8(2), 2001, pp. 441-444

Abstract

Institutions that treat patients with lymphoma must know their local therapy results and adapt their treatment strategies accordingly. To allow the application of the International Prognostic Factor Index (IPI) in institutions where some of the data necessary are not available, we devised an approach by which the missing data would not impair the applicability of the index. We also collapsed the four categories of the IPI into two categories, and applied this adapted IPI to patients with aggressive non-Hodgkin's lymphoma treated in a public university hospital. Among the 72 patients treated with combination chemotherapy regimens containing doxorubicin, the followingoutcomes were observed for low and high risk groups, respectively: complete remission rates were 62% and 45% (p=0.2), overall survival rates were 48%and 14% (p=0.0098) and failure-free survival rates were 44% and 17% (p=0.03). This adapted IPI was very effective in predicting the outcome in the patients studied. The survival rates observed in our population were substantially lower than the rates reported in the IPI study. Patient selection might have played an important role in this difference, although other factorsrelated to the social acid general health status of the patients treated need to be prospectively studied.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 21:35:56