Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Prognostic value of thymidine phosphorylase immunostaining in patients with uterine cervical cancer treated concurrently with doxifluridine, radiotherapy and immunotherapy
Autore:
Sato, S; Yajima, A; Sasaki, H; Mizutani, K; Honjo, H; Yamamoto, K; Ozaki, M; Hasegawa, K; Kudo, T; Yakushiji, M; Hatae, M; Noda, K;
Indirizzi:
Tohoku Univ, Fac Med,Sch Med, Dept Obstet & Gynecol, Aoba Ku, Sendai, Miyagi 9808574, Japan Tohoku Univ Sendai Miyagi Japan 9808574 Ku, Sendai, Miyagi 9808574, Japan Jikei Univ, Sch Med, Minato Ku, Tokyo 1050003, Japan Jikei Univ Tokyo Japan 1050003 Sch Med, Minato Ku, Tokyo 1050003, Japan Tokyo Metropolitan Komagome Hosp, Bunkyo Ku, Tokyo 1130021, Japan Tokyo Metropolitan Komagome Hosp Tokyo Japan 1130021 okyo 1130021, Japan Kyoto Prefectural Univ, Sch Med, Kamigyo Ku, Kyoto 6020841, Japan Kyoto Prefectural Univ Kyoto Japan 6020841 igyo Ku, Kyoto 6020841, Japan Kinki Univ, Sch Med, Osaka 5898511, Japan Kinki Univ Osaka Japan 5898511Kinki Univ, Sch Med, Osaka 5898511, Japan Bellland Hosp, Osaka 5998247, Japan Bellland Hosp Osaka Japan 5998247Bellland Hosp, Osaka 5998247, Japan Hyogo Med Ctr Adults, Akashi, Hyogo 6730021, Japan Hyogo Med Ctr Adults Akashi Hyogo Japan 6730021 shi, Hyogo 6730021, Japan Okayama Univ, Sch Med, Okayama 7000914, Japan Okayama Univ Okayama Japan7000914 Univ, Sch Med, Okayama 7000914, Japan Kurume Univ, Fac Med, Fukuoka 8300011, Japan Kurume Univ Fukuoka Japan 8300011 Univ, Fac Med, Fukuoka 8300011, Japan Kagoshima City Hosp, Kagoshima 8928580, Japan Kagoshima City Hosp Kagoshima Japan 8928580 sp, Kagoshima 8928580, Japan
Titolo Testata:
ONCOLOGY REPORTS
fascicolo: 2, volume: 8, anno: 2001,
pagine: 239 - 244
SICI:
1021-335X(200103/04)8:2<239:PVOTPI>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
CELL GROWTH-FACTOR; ANGIOGENIC ACTIVITY; 5'-DEOXY-5-FLUOROURIDINE; EXPRESSION; SENSITIVITY; PREDICTION; CARCINOMA; TISSUES;
Keywords:
thymidine phosphorylase; immunohistochemistry; prognosis; uterine cervical cancer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Sato, S Tohoku Univ, Fac Med,Sch Med, Dept Obstet & Gynecol, Aoba Ku, 1-1 Seiryo Machi, Sendai, Miyagi 9808574, Japan Tohoku Univ 1-1 Seiryo Machi Sendai Miyagi Japan 9808574 74, Japan
Citazione:
S. Sato et al., "Prognostic value of thymidine phosphorylase immunostaining in patients with uterine cervical cancer treated concurrently with doxifluridine, radiotherapy and immunotherapy", ONCOL REP, 8(2), 2001, pp. 239-244

Abstract

Thymidine phosphorylase (dThdPase) is reportedly identical to platelet-derived endothelial cell growth factor (PD-ECGF). We conducted immunohistochemical staining of dThdPase to assess correlation between its expression in cancer tissue and efficacy of a combination therapy with 5'-DFUR, radiotherapy and sizofilan (SPG) in uterine cervical cancer patients. No difference in response rates was observed between dThdPase positive and negative tumor and stromal cells. Survival curves significantly differed between stromal dThdPase positive and negative groups (p=0.032). Results showed that dThdPase immunostaining is possibly prognostic and predictive in determining success of the combination therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 04:38:23