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Titolo:
What have we learned about cognition in myasthenia gravis?: a review of methods and results
Autore:
Paul, RH; Cohen, RA; Zawacki, T; Gilchrist, JM; Aloia, MS;
Indirizzi:
Miriam Hosp, Brown Med Sch, Div Behav & Prevent Med, Providence, RI 02906 USA Miriam Hosp Providence RI USA 02906 Prevent Med, Providence, RI 02906 USA
Titolo Testata:
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
fascicolo: 1, volume: 25, anno: 2001,
pagine: 75 - 81
SICI:
0149-7634(200101)25:1<75:WHWLAC>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
AFFECTIVE-DISORDERS; SLEEP-APNEA; MEMORY; BRAIN; ACETYLCHOLINE; PERFORMANCE; DYSFUNCTION; ANTIBODIES; DEPRESSION; RECEPTORS;
Keywords:
myasthenia gravis; cognition; review; acetylcholine;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Paul, RH Miriam Hosp, Brown Med Sch, Div Behav & Prevent Med, Fain 328,164Summit Ave, Providence, RI 02906 USA Miriam Hosp Fain 328,164 Summit Ave Providence RI USA 02906 6 USA
Citazione:
R.H. Paul et al., "What have we learned about cognition in myasthenia gravis?: a review of methods and results", NEUROSCI B, 25(1), 2001, pp. 75-81

Abstract

Most individuals with myasthenia gravis (MG) complain of cognitive impairment, but empirical studies of cognition in MG have produced mixed results. In the present review, we critically examined the methodology and results of previous studies that investigated cognition in MG. Results from our review revealed that none of the studies met at least 50% of criteria under review. The most common shortcomings of previous studies included small samplesize, no exclusion for visual difficulties in patients, inadequate assessment of mood, and poor control for prednisone use. Despite these methodological difficulties, mild impairments on measures of learning have been identified. These findings need to be replicated with adequate control of potential confounds before any conclusions can be made regarding cognition in thisdisease. Suggestions for design of future studies are provided. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 12:34:23