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Titolo:
Automated quantitative gait analysis during overground locomotion in the rat: Its application to spinal cord contusion and transection injuries
Autore:
Hamers, FPT; Lankhorst, AJ; Van Laar, TJ; Veldhuis, WB; Gispen, WH;
Indirizzi:
Univ Utrecht, Med Ctr, Dept Med Pharmacol, Rudolf Magnus Inst Neurosci, NL-3564 CG Utrecht, Netherlands Univ Utrecht Utrecht Netherlands NL-3564 CG3564 CG Utrecht, Netherlands
Titolo Testata:
JOURNAL OF NEUROTRAUMA
fascicolo: 2, volume: 18, anno: 2001,
pagine: 187 - 201
SICI:
0897-7151(200102)18:2<187:AQGADO>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
WALKING TRACKS; RECOVERY; HEMISECTION; PATTERNS; REPAIR; CATS;
Keywords:
functional studies; gait analysis; interlimb coordination; spinal cord contusion; spinal cord lesions; spinal cord transection;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Hamers, FPT Univ Utrecht, Med Ctr, Dept Med Pharmacol, Rudolf Magnus Inst Neurosci, Univ Weg 100, NL-3564 CG Utrecht, Netherlands Univ Utrecht Univ Weg 100 Utrecht Netherlands NL-3564 CG ands
Citazione:
F.P.T. Hamers et al., "Automated quantitative gait analysis during overground locomotion in the rat: Its application to spinal cord contusion and transection injuries", J NEUROTRAU, 18(2), 2001, pp. 187-201

Abstract

Analysis of locomotion is an important tool in the study of peripheral andcentral nervous system damage. Most locomotor scoring systems in rodents are based either upon open field locomotion assessment, for example, the BBBscore or upon foot print analysis. The former yields a semiquantitative description of locomotion as a whole, whereas the latter generates quantitative data on several selected gait parameters. In this paper, we describe theuse of a newly developed gait analysis method that allows easy quantitation of a large number of locomotion parameters during walkway crossing. We were able to extract data on interlimb coordination, swing duration, paw print areas (total over stance, and at 20-msec time resolution), stride length,and base of support: Similar data can not be gathered by any single previously described method. We compare changes in gait parameters induced by twodifferent models of spinal cord injury in rats, transection of the dorsal half of the spinal cord and spinal cord contusion injury induced by the NYUor MASCIS device. Although we applied this method to rats with spinal cordinjury, the usefulness of this method is not limited to rats or to the investigation of spinal cord injuries alone.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 01:08:52