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Titolo:
Enhanced production of vascular endothelial growth factor by human monocytic cells stimulated with endotoxin through transcription factor SP-1
Autore:
Sakuta, T; Matsushita, K; Yamaguchi, N; Oyama, T; Motani, R; Koga, T; Nagaoka, S; Abeyama, K; Maruyama, K; Takada, H; Torii, M;
Indirizzi:
Kagoshima Univ, Sch Dent, Dept Operat Dent & Endodontol, Kagoshima 8908544, Japan Kagoshima Univ Kagoshima Japan 8908544 odontol, Kagoshima 8908544, Japan Kyushu Univ, Fac Dent, Dept Prevent Dent, Fukuoka 8128582, Japan Kyushu Univ Fukuoka Japan 8128582 t Prevent Dent, Fukuoka 8128582, Japan Kagoshima Univ, Sch Med, Dept Clin Lab Med, Kagoshima 8908520, Japan Kagoshima Univ Kagoshima Japan 8908520 Lab Med, Kagoshima 8908520, Japan Tohoku Univ, Sch Dent, Dept Microbiol & Immunol, Sendai, Miyagi 9808575, Japan Tohoku Univ Sendai Miyagi Japan 9808575 ol, Sendai, Miyagi 9808575, Japan
Titolo Testata:
JOURNAL OF MEDICAL MICROBIOLOGY
fascicolo: 3, volume: 50, anno: 2001,
pagine: 233 - 237
SICI:
0022-2615(200103)50:3<233:EPOVEG>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
NECROSIS-FACTOR-ALPHA; FACTOR VEGF; EXPRESSION; GENE; LIPOPOLYSACCHARIDE; KERATINOCYTES; BIOLOGY; HYPOXIA; KINASE; SYSTEM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Torii, M Kagoshima Univ, Sch Dent, Dept Operat Dent & Endodontol, Kagoshima 8908544, Japan Kagoshima Univ Kagoshima Japan 8908544 Kagoshima 8908544, Japan
Citazione:
T. Sakuta et al., "Enhanced production of vascular endothelial growth factor by human monocytic cells stimulated with endotoxin through transcription factor SP-1", J MED MICRO, 50(3), 2001, pp. 233-237

Abstract

The effect of endotoxin on the regulation of vascular endothelial growth factor (VEGF) mRNA expression in human monocytic (THP-1) cells was examined. Endotoxic lipopolysaccharide (LPS) from Escherichia coli and synthetic E, coli-type lipid A (LA-15-PP) enhanced VEGF mRNA expression. LPS-induced VEGF mRNA accumulation was regulated, at least in part, at the transcriptionallevel. Enhancement of VEGF gene expression by LPS was shown by gel shift analysis and use of transcription factor Inhibitors to be mediated via the activation of SP-1.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 13:10:47