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Titolo:
Re-analysis of human immunodeficiency virus type 1 isolates from Cyprus and Greece, initially designated 'subtype I', reveals a unique complex A/G/H/K/? mosaic pattern
Autore:
Paraskevis, D; Magiorkinis, M; Vandamme, AM; Kostrikis, LG; Hatzakis, A;
Indirizzi:
Univ Athens, Sch Med, Dept Hyg & Epidemiol, Natl Retrovirus Reference Ctr,GR-11527 Athens, Greece Univ Athens Athens Greece GR-11527 Reference Ctr,GR-11527 Athens, Greece Katholieke Univ Leuven, Rega Inst Med Res, Louvain, Belgium Katholieke Univ Leuven Louvain Belgium a Inst Med Res, Louvain, Belgium Katholieke Univ Leuven, Univ Hosp, Louvain, Belgium Katholieke Univ Leuven Louvain Belgium ven, Univ Hosp, Louvain, Belgium Rockefeller Univ, Aaron Diamond AIDS Res Ctr, New York, NY 10016 USA Rockefeller Univ New York NY USA 10016 DS Res Ctr, New York, NY 10016 USA
Titolo Testata:
JOURNAL OF GENERAL VIROLOGY
, volume: 82, anno: 2001,
parte:, 3
pagine: 575 - 580
SICI:
0022-1317(200103)82:<575:ROHIVT>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
INJECTING DRUG-USERS; HIV TYPE-1; SEQUENCE; EPIDEMIC; GENOME; IDENTIFICATION; RECOMBINANTS; THAILAND; AFRICA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Hatzakis, A Univ Athens, Sch Med, Dept Hyg & Epidemiol, Natl Retrovirus Reference Ctr,M Asias 75, GR-11527 Athens, Greece Univ Athens M Asias 75 Athens Greece GR-11527 Athens, Greece
Citazione:
D. Paraskevis et al., "Re-analysis of human immunodeficiency virus type 1 isolates from Cyprus and Greece, initially designated 'subtype I', reveals a unique complex A/G/H/K/? mosaic pattern", J GEN VIROL, 82, 2001, pp. 575-580

Abstract

Human immunodeficiency virus type 1 (HIV-1) has been classified into threemain groups and 11 distinct subtypes. Moreover, several circulating recombinant forms (CRFs) of HIV-1 have been recently documented to have spread widely causing extensive HIV-1 epidemics. A subtype, initially designated I (CRF04_cpx), was documented in Cyprus and Greece and was found to comprise regions of sequence derived from subtypes A and G as well as regions of unclassified sequence. Reanalysis of the three full-length CRF04_cpx sequences that were available revealed a mosaic genomic organization of unique complexity comprising regions of sequence from at least five distinct subtypes, A, G, H, K and unclassified regions. These strains account for approximately2% of the total HIV-1-infected population in Greece, thus providing evidence of the great capability of HIV-1 to recombine and produce highly divergent strains which can be spread successfully through different infection routes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 14:29:03