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Titolo:
Molecular heterogeneity of bla(VIM-2)-containing integrons from Pseudomonas aeruginosa plasmids encoding the VIM-2 metallo-beta-lactamase
Autore:
Pallecchi, L; Riccio, ML; Docquier, JD; Fontana, R; Rossolini, GM;
Indirizzi:
Univ Siena, Dipartimento Biol Mol, Sez Microbiol, I-53100 Siena, Italy Univ Siena Siena Italy I-53100 Mol, Sez Microbiol, I-53100 Siena, Italy Univ Verona, Dipartimento Patol, Sez Microbiol, I-37134 Verona, Italy UnivVerona Verona Italy I-37134 l, Sez Microbiol, I-37134 Verona, Italy
Titolo Testata:
FEMS MICROBIOLOGY LETTERS
fascicolo: 2, volume: 195, anno: 2001,
pagine: 145 - 150
SICI:
0378-1097(20010220)195:2<145:MHOBIF>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
MOBILE GENE CASSETTES; CLINICAL ISOLATE; RECOMBINATION; RESISTANCE; CARBAPENEMASE; BLA(IMP); ELEMENT; BORNE;
Keywords:
Pseudomonas aeruginosa; plasmid; metallo-beta-lactamase;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Rossolini, GM Univ Siena, Dipartimento Biol Mol, Sez Microbiol, Via Laterina 8, I-53100 Siena, Italy Univ Siena Via Laterina 8 Siena Italy I-53100 Siena, Italy
Citazione:
L. Pallecchi et al., "Molecular heterogeneity of bla(VIM-2)-containing integrons from Pseudomonas aeruginosa plasmids encoding the VIM-2 metallo-beta-lactamase", FEMS MICROB, 195(2), 2001, pp. 145-150

Abstract

A bla(VIM-2) metallo-beta -lactamase determinant, identical to that previously identified in Pseudomonas aeruginosa COL-1 isolate from a French hospital, was detected on a 28-kb plasmid carried by a nosocomial isolate of P. aeruginosa from Verona, Italy. In this plasmid the bla(VIM-2) determinant was inserted into a class 1 integron of original structure, named In72, thatcontains a partially deleted int11 integrase gene and two gene cassettes. The first cassette carries an aacA4 aminoglycoside acetyl transferase determinant. The second cassette carries a bla(VIM-2): determinant followed by apartially deleted attC site. The structure of In72 was notably different from that of In56, the bla(VIM-2)- containing integron found in the COL-1 isolate, revealing the existence of molecular heterogeneity among bla(VIM-2)-containing integrons in clinical isolates of P. aeruginosa from Europe. (C)2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/04/20 alle ore 01:25:02