Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Utility of Tc-99m-HM-PAO SPECT hippocampal image to diagnose early stages of Alzheimer's disease using semiquantitative analysis
Autore:
Nebu, A; Ikeda, M; Fukuhara, R; Komori, K; Maki, N; Hokoishi, K; Shigenobu, K; Kikuchi, T; Tanabe, H;
Indirizzi:
Ehime Univ, Sch Med, Dept Neuropsychiat, Shigenobu, Ehime 7910295, Japan Ehime Univ Shigenobu Ehime Japan 7910295 Shigenobu, Ehime 7910295, Japan Ehime Univ, Sch Med, Dept Radiol, Shigenobu, Ehime 7910295, Japan Ehime Univ Shigenobu Ehime Japan 7910295 Shigenobu, Ehime 7910295, Japan
Titolo Testata:
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
fascicolo: 2, volume: 12, anno: 2001,
pagine: 153 - 157
SICI:
1420-8008(200103/04)12:2<153:UOTSHI>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEMORY; DEMENTIA; SCALE;
Keywords:
99mTc-HM-PAO SPECT hippocampal image; Alzheimer's disease, early stages; diagnosis, early; semiquantitative analysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Ikeda, M Ehime Univ, Sch Med, Dept Neuropsychiat, Shigenobu, Ehime 7910295, Japan Ehime Univ Shigenobu Ehime Japan 7910295 u, Ehime 7910295, Japan
Citazione:
A. Nebu et al., "Utility of Tc-99m-HM-PAO SPECT hippocampal image to diagnose early stages of Alzheimer's disease using semiquantitative analysis", DEMENT G C, 12(2), 2001, pp. 153-157

Abstract

Objective: Examination of the utility of Tc-99m-hexamethylpropylene amine oxide (Tc-99m-HM-PAO) SPECT hippocampal image to diagnose early stages of Alzheimer's disease (AD) using semiquantitative analysis,Subjects: 10 early-stage AD patients and 8 normal sex-matched elderly controls. Setting: Outpatient division of the Ehime University Hospital. Method: We performed Tc-99m-HM-PAO SPECT perfusion imaging in each subject, A semiquantitative method of assessing regional variation was used, The regions of interest for temporal regions were set at images parallel to the long axis of the hippocampal formation which were reconstructed at 30 degrees negative to the orbitomeatal line and those for other regions were set on ordinary transaxial images. Results: The regional cerebral blood flow ratio of the bilateral medial temporal lobe at the hippocampal image was significantly fewer in the AD subjects than in the normally aged controls without ant other differences in ordinary transaxial images. Conclusion: This study suggests that Tc-99m-HM-PAO SPECT hippocampal images might be a helpful tool for the diagnosis of very-early-stage AD. Copyright (C) 2001 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/09/19 alle ore 23:00:47