Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Extracellular amino acid profiles in the paraventricular nucleus of the rat hypothalamus are influenced by diet composition
Autore:
Choi, YH; Fletcher, PJ; Anderson, GH;
Indirizzi:
Univ Toronto, Fac Med, Dept Nutr Sci, Toronto, ON M5S 3E2, Canada Univ Toronto Toronto ON Canada M5S 3E2 r Sci, Toronto, ON M5S 3E2, Canada Ctr Addict & Mental Hlth, Sect Biopsychol, Toronto, ON M5T 1R8, Canada CtrAddict & Mental Hlth Toronto ON Canada M5T 1R8 to, ON M5T 1R8, Canada
Titolo Testata:
BRAIN RESEARCH
fascicolo: 2, volume: 892, anno: 2001,
pagine: 320 - 328
SICI:
0006-8993(20010223)892:2<320:EAAPIT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-BRAIN-BARRIER; FREELY MOVING RATS; FOOD-INTAKE; SEROTONIN CONTENT; PROTEIN-INTAKE; MICRODIALYSIS; PLASMA; INGESTION; RELEASE; PERMEABILITY;
Keywords:
microdialysis; feeding behavior; tryptophan to branched-chain amino acid ratio serotonin; protein-free; high carbohydrate diet; high protein low carbohydrate diet;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Anderson, GH Univ Toronto, Fac Med, Dept Nutr Sci, Toronto, ON M5S 3E2, Canada Univ Toronto Toronto ON Canada M5S 3E2 o, ON M5S 3E2, Canada
Citazione:
Y.H. Choi et al., "Extracellular amino acid profiles in the paraventricular nucleus of the rat hypothalamus are influenced by diet composition", BRAIN RES, 892(2), 2001, pp. 320-328

Abstract

One possible mechanism by which food consumption signals feeding centers is through the resulting changes in amino acid profiles in the brain. In this study we examined the effect of voluntary consumption of a 50% protein diet or a 0% protein (carbohydrate) diet on extracellular amino acid profilesin the hypothalamic paraventricular nucleus (PVN) of freely moving rats from 1800 to 2100 h. Dialysates were continuously collected via microdialysisprobes inserted in the PVN at 1500 h. Extracellular concentrations of isoleucine, leucine, methionine. tyrosine and valine were elevated within the first or second 20 min following the start of the 50% protein diet (P<0.05). The ratio of tryptophan to the total branched-chain amino acids (BCAA) in extracellular fluid increased following consumption of the carbohydrate diet (P<0.05), but decreased after the protein diet. An elevated ratio of tyrosine to BCAA was observed at the end of the measurement following the protein-free meal. It is concluded that amino acid concentrations in extracellular fluid of the PVN change rapidly after food consumption and that the changes are influenced by dietary composition. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 01:47:39