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Titolo:
Is there a relationship between cognitive dysfunction and systemic inflammatory response after cardiopulmonary bypass?
Autore:
Westaby, S; Saatvedt, K; White, S; Katsumata, T; van Oeveren, W; Halligan, PW;
Indirizzi:
John Radcliffe Hosp, Oxford Heart Ctr, Oxford OX3 9DU, England John Radcliffe Hosp Oxford England OX3 9DU Ctr, Oxford OX3 9DU, England Univ Groningen, Groningen, Netherlands Univ Groningen Groningen Netherlands Groningen, Groningen, Netherlands Univ Wales Coll Cardiff, Dept Psychol, Cardiff, S Glam, Wales Univ Wales Coll Cardiff Cardiff S Glam Wales hol, Cardiff, S Glam, Wales
Titolo Testata:
ANNALS OF THORACIC SURGERY
fascicolo: 2, volume: 71, anno: 2001,
pagine: 667 - 672
SICI:
0003-4975(200102)71:2<667:ITARBC>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY BYPASS; ACTIVATION; COMPLEMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Westaby, S John Radcliffe Hosp, Oxford Heart Ctr, Oxford OX3 9DU, England John Radcliffe Hosp Oxford England OX3 9DU d OX3 9DU, England
Citazione:
S. Westaby et al., "Is there a relationship between cognitive dysfunction and systemic inflammatory response after cardiopulmonary bypass?", ANN THORAC, 71(2), 2001, pp. 667-672

Abstract

Background. The systemic inflammatory reaction (SIR) is assumed to be one of the factors that causes cerebral dysfunction after cardiopulmonary bypass (CPB). The aim of the present study was to evaluate the relationship between the SIR and postoperative cognitive performance at 5 days and 3 months. Methods. One hundred patients undergoing coronary artery bypass grafting were studied. Inflammatory markers and markers of coagulation and fibrinolysis were determined at several time points during and after the operation. Correlation analysis between maximum levels of the different markers and early and late performance was performed. Results. No overall association was found between the maximum levels of the inflammatory markers and early and late function. Conclusions. Notwithstanding limitations of statistical power established markers of systemic inflammatory reaction showed no relationship with outcome at 5-day or 3-month follow-up in this subset of patients. (C) 2001 by The Society of Thoracic Surgeons.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 15:51:42