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OPAC HELP

Titolo:
Chronic graft-versus-host disease after hematopoietic cell transplantationpresenting as an acute hepatitis
Autore:
Malik, AH; Collins, RH; Saboorian, MH; Lee, WM;
Indirizzi:
Univ Texas, SW Med Ctr, Div Digest & Liver Dis, Dallas, TX 75390 USA Univ Texas Dallas TX USA 75390 v Digest & Liver Dis, Dallas, TX 75390 USA Univ Texas, SW Med Ctr, Div Hematol Oncol, Dept Internal Med, Dallas, TX 75390 USA Univ Texas Dallas TX USA 75390 l, Dept Internal Med, Dallas, TX 75390 USA Univ Texas, SW Med Ctr, Dept Pathol, Dallas, TX 75390 USA Univ Texas Dallas TX USA 75390 Med Ctr, Dept Pathol, Dallas, TX 75390 USA
Titolo Testata:
AMERICAN JOURNAL OF GASTROENTEROLOGY
fascicolo: 2, volume: 96, anno: 2001,
pagine: 588 - 590
SICI:
0002-9270(200102)96:2<588:CGDAHC>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE-MARROW TRANSPLANTATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
7
Recensione:
Indirizzi per estratti:
Indirizzo: Lee, WM Univ Texas, SW Med Ctr, Div Digest & Liver Dis, 5323 Harry Hines Blvd, Dallas, TX 75390 USA Univ Texas 5323 Harry Hines Blvd Dallas TX USA 75390 TX 75390 USA
Citazione:
A.H. Malik et al., "Chronic graft-versus-host disease after hematopoietic cell transplantationpresenting as an acute hepatitis", AM J GASTRO, 96(2), 2001, pp. 588-590

Abstract

A variety of illnesses involving the gut and liver follow hematopoietic cell transplantation (HCT). A 20 yr-old white male developed severe acute hepatitis 36 wk (day 252) after matched, unrelated, allogeneic HCT for chronicmyelogenous leukemia (CML). Mild skin graft-versus-host disease (GVHD) hadoccurred at about 20 wk (day 140) after transplant. Liver biopsy showed bile duct injury and a diffuse lobular injury pattern most consistent with a GVHD variant and not reminiscent of drug-induced or viral hepatitis. No findings suggestive of herpesvirus, adenovirus, or varicella-zoster virus werefound. High-dose steroids resulted in marked improvement of his liver enzyme levels. We report this patient as representing the acute hepatitic presentation of chronic GVHD of the liver.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/10/20 alle ore 12:28:02