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Titolo:
Risk factors for active syphilis and TPHA seroconversion in a rural African population
Autore:
Todd, J; Munguti, K; Grosskurth, H; Mngara, J; Changalucha, J; Mayaud, P; Mosha, F; Gavyole, A; Mabey, D; Hayes, R;
Indirizzi:
Univ London London Sch Hyg & Trop Med, London WC1E 7HT, England Univ London London Sch Hyg & Trop Med London England WC1E 7HT T, England Natl Inst Med Res, Mwanza, Tanzania Natl Inst Med Res Mwanza TanzaniaNatl Inst Med Res, Mwanza, Tanzania African Med & Res Fdn, Mwanza, Tanzania African Med & Res Fdn Mwanza Tanzania n Med & Res Fdn, Mwanza, Tanzania Reg Med Off, Mwanza, Tanzania Reg Med Off Mwanza TanzaniaReg Med Off, Mwanza, Tanzania
Titolo Testata:
SEXUALLY TRANSMITTED INFECTIONS
fascicolo: 1, volume: 77, anno: 2001,
pagine: 37 - 45
SICI:
1368-4973(200102)77:1<37:RFFASA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEXUALLY-TRANSMITTED DISEASES; NORTH-WESTERN TANZANIA; RANDOMIZED CONTROLLED TRIAL; HIV-INFECTION; COMMUNITY TRIAL; PREVALENCE; BEHAVIOR; HEALTH; IMPACT; TRANSMISSION;
Keywords:
syphilis; risk factors; Africa;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Todd, J Univ London London Sch Hyg & Trop Med, Keppel St, London WC1E 7HT,England Univ London London Sch Hyg & Trop Med Keppel St London England WC1E 7HT
Citazione:
J. Todd et al., "Risk factors for active syphilis and TPHA seroconversion in a rural African population", SEX TRANS I, 77(1), 2001, pp. 37-45

Abstract

Objectives: Syphilis is an important cause of morbidity in sub-Saharan Africa, and a cofactor for the sexual transmission of HIV. A better understanding of the prevalence and risk factors of syphilis in African populations would help to formulate effective interventions for its prevention and treatment. Methods: The prevalence and incidence of syphilis were obtained from a cohort recruited in Mwanza, Tanzania. Two unmatched case-control studies nested within the cohort provide information on potential risk factors. Results: The prevalence of active syphilis (TPHA positive and RPR positiveany titre) was 7.5% in men and 9.1% in women, but in youths (aged 15-19 years) the prevalence was higher in women (6.6%) than in men (2.0%). The incidence of TPHA seroconversion was highest in women aged 15-19 at 3.4% per year, and around 2% per year at all ages among men. A higher prevalence of syphilis was found in those currently divorced or widowed (men: OR=1.61, women: OR=2.78), and those previously divorced or widowed (men: OR=1.51, women:OR=1.85). Among men, prevalence was associated with lack of circumcision (OR=1.89), traditional religion (OR=1.55), and reporting five or more partners during the past year (OR=1.81) while incidence was associated with no primary education (OR=2.17), farming (OR=3.85), and a self perceived high risk of STD (OR=3.56). In women, prevalence was associated with no primary education (OR=2.13), early sexual debut (OR=1.59), and a self perceived high risk of STD (OR=3.57), while incidence was associated with living away from the community (OR=2.72). Conclusion: The prevalence and incidence of syphilis remain high in this rural African population. More effort is needed to promote safer sexual behaviour, and to provide effective, accessible treatment. The high incidence of syphilis in young women calls for sexual health interventions targeted atadolescents.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 18:22:26