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Titolo:
The MLA6 coiled-coil, NBS-LRR protein confers AvrMla6-dependent resistancespecificity to Blumeria graminis f. sp hordei in barley and wheat
Autore:
Halterman, D; Zhou, FS; Wei, FS; Wise, RP; Schulze-Lefert, P;
Indirizzi:
Iowa State Univ, USDA ARS, Ames, IA 50011 USA Iowa State Univ Ames IA USA50011 tate Univ, USDA ARS, Ames, IA 50011 USA Iowa State Univ, Dept Plant Pathol, Ames, IA 50011 USA Iowa State Univ Ames IA USA 50011 , Dept Plant Pathol, Ames, IA 50011 USA Iowa State Univ, Interdepartmental Genet Program, Ames, IA 50011 USA Iowa State Univ Ames IA USA 50011 ental Genet Program, Ames, IA 50011 USA John Innes Ctr Plant Sci Res, Sainsbury Lab, Norwich NR4 7UH, Norfolk, England John Innes Ctr Plant Sci Res Norwich Norfolk England NR4 7UH olk, England
Titolo Testata:
PLANT JOURNAL
fascicolo: 3, volume: 25, anno: 2001,
pagine: 335 - 348
SICI:
0960-7412(200102)25:3<335:TMCNPC>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
POWDERY MILDEW RESISTANCE; TOBACCO MOSAIC-VIRUS; TRITICUM-AESTIVUM L; FLAX RUST RESISTANCE; FOR-GENE CONCEPT; DISEASE-RESISTANCE; ERYSIPHE-GRAMINIS; 5'-UNTRANSLATED REGION; DIVERGENT SELECTION; ALLELIC VARIATION;
Keywords:
CC-NBS-LRR; Rar1-dependent signaling; heterologous resistance specificity; alternative splicing;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
74
Recensione:
Indirizzi per estratti:
Indirizzo: Wise, RP Iowa State Univ, USDA ARS, Ames, IA 50011 USA Iowa State Univ Ames IA USA 50011 , USDA ARS, Ames, IA 50011 USA
Citazione:
D. Halterman et al., "The MLA6 coiled-coil, NBS-LRR protein confers AvrMla6-dependent resistancespecificity to Blumeria graminis f. sp hordei in barley and wheat", PLANT J, 25(3), 2001, pp. 335-348

Abstract

The barley Mla locus confers multiple resistance specificities to the obligate fungal biotroph, Blumeria (= Erysiphe) graminis f. sp. hordei. Interspersed within the 240 kb Mla complex are three families of resistance gene homologs (RGHs). Probes from the Mla-RGH1 family were used to identify threeclasses of cDNAs. The first class is predicted to encode a full-length CC-NBS-LRR protein and the other two classes contain alternatively spliced, truncated variants. Utilizing a cosmid that contains a gene corresponding to the full-length candidate cDNA, two single-cell expression assays were usedto demonstrate complementation of AvrMla6-dependent, resistance specificity to B. graminis in barley and wheat. The first of these assays was also used to substantiate previous genetic data that the Mla6 allele requires the signaling pathway component, Rar1, for function. Computational analysis of MLA6 and the Rar1-independent, MLA1 protein reveals 91.2% identity and shows that the LRR domain is subject to diversifying selection. Our findings demonstrate that highly related CC-NBS-LRR proteins encoded by alleles of theMla locus can dictate similar powdery mildew resistance phenotypes yet still require distinct downstream signaling components.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 04:21:03