Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Searching for human longevity genes: The future history of gerontology in the post-genomic era
Autore:
Barzilai, N; Shuldiner, AR;
Indirizzi:
Yeshiva Univ Albert Einstein Coll Med, Dept Med, Div Geriatr, Bronx, NY 10461 USA Yeshiva Univ Albert Einstein Coll Med Bronx NY USA 10461 nx, NY 10461 USA Yeshiva Univ Albert Einstein Coll Med, Dept Med, Div Endocrinol, Bronx, NY10461 USA Yeshiva Univ Albert Einstein Coll Med Bronx NY USA 10461 onx, NY10461 USA Yeshiva Univ Albert Einstein Coll Med, Ctr Diabet Res & Training, Bronx, NY 10461 USA Yeshiva Univ Albert Einstein Coll Med Bronx NY USA 10461 nx, NY 10461 USA Univ Maryland, Div Endocrinol Diabet & Nutr, Baltimore, MD 21201 USA Univ Maryland Baltimore MD USA 21201 abet & Nutr, Baltimore, MD 21201 USA Baltimore Vet Adm Med Ctr, Ctr Geriatr Res Educ & Clin, Baltimore, MD USA Baltimore Vet Adm Med Ctr Baltimore MD USA duc & Clin, Baltimore, MD USA
Titolo Testata:
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
fascicolo: 2, volume: 56, anno: 2001,
pagine: M83 - M87
SICI:
1079-5006(200102)56:2<M83:SFHLGT>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIFE-SPAN; CALORIC RESTRICTION; BETA(3)-ADRENERGIC-RECEPTOR GENE; CAENORHABDITIS-ELEGANS; OXIDATIVE STRESS; INSULIN; CENTENARIANS; TELOMERASE; RESISTANCE; EXTENSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Barzilai, N Yeshiva Univ Albert Einstein Coll Med, Dept Med, Div Geriatr, Belfer Bldg 701,1300 Morris Pk Ave, Bronx, NY 10461 USA Yeshiva Univ AlbertEinstein Coll Med Belfer Bldg 701,1300 Morris Pk Ave Bronx NY USA 10461
Citazione:
N. Barzilai e A.R. Shuldiner, "Searching for human longevity genes: The future history of gerontology in the post-genomic era", J GERONT A, 56(2), 2001, pp. M83-M87

Abstract

Over the last 30 years, a number of genetic and environmental factors thatlead to decreased length of life have been identified. Unfortunately, muchless progress has been achieved in identifying genes associated with longevity that protect From common diseases or slow the aging process. Recent compelling evidence supports a role for important genetic and environmental interactions on longevity in lower organisms. Although less is known in humans, commonality in molecular and biological processes, evolutionary arguments, and epidemiological data would strongly suggest that similar mechanismsalso apply. The completion of the Human Genome Project and the rapid innovations in technology will make possible the identification of human longevity-assurance genes. This article reviews such evidence, its implications for the identification of human longevity-assurance genes, and the significance of finding longevity genes to human health and disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 12:42:28