Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Corticobasal degeneration presenting with nonfluent primary progressive aphasia: a clinicopathological study
Autore:
Mimura, M; Oda, T; Tsuchiya, K; Kato, M; Ikeda, K; Hori, K; Kashima, H;
Indirizzi:
Showa Univ, Sch Med, Dept Neuropsychiat, Shinagawa Ku, Tokyo 1428666, Japan Showa Univ Tokyo Japan 1428666 chiat, Shinagawa Ku, Tokyo 1428666, Japan Natl Shimofusa Sanatorium, Dept Neuropsychiat, Chiba, Japan Natl ShimofusaSanatorium Chiba Japan Dept Neuropsychiat, Chiba, Japan Tokyo Metropolitan Matsuzawa Hosp, Dept Lab Med & Pathol, Tokyo, Japan Tokyo Metropolitan Matsuzawa Hosp Tokyo Japan ed & Pathol, Tokyo, Japan Tokyo Inst Psychiat, Dept Neuropathol, Tokyo, Japan Tokyo Inst Psychiat Tokyo Japan sychiat, Dept Neuropathol, Tokyo, Japan Ichikawa Gen Hosp, Tokyo Dent Coll, Dept Neuropsychiat, Chiba, Japan Ichikawa Gen Hosp Chiba Japan nt Coll, Dept Neuropsychiat, Chiba, Japan Keio Univ, Sch Med, Dept Neuropsychiat, Tokyo, Japan Keio Univ Tokyo Japan o Univ, Sch Med, Dept Neuropsychiat, Tokyo, Japan
Titolo Testata:
JOURNAL OF THE NEUROLOGICAL SCIENCES
fascicolo: 1, volume: 183, anno: 2001,
pagine: 19 - 26
SICI:
0022-510X(20010115)183:1<19:CDPWNP>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
PICKS-DISEASE; NEURONAL ACHROMASIA; CORTICONIGRAL DEGENERATION; NEUROFIBRILLARY TANGLES; ALZHEIMERS-DISEASE; SUPRANUCLEAR PALSY; PATHOLOGY; LANGUAGE; DEMENTIA; PROFILE;
Keywords:
corticobasal degeneration; primary progressive aphasia; frontal lobe dementia; Pick's disease; nonfluent aphasia; cytoskeletal abnormality;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Mimura, M Showa Univ, Sch Med, Dept Neuropsychiat, Shinagawa Ku, 1-5-8 Hatanodai, Tokyo 1428666, Japan Showa Univ 1-5-8 Hatanodai Tokyo Japan 1428666 o 1428666, Japan
Citazione:
M. Mimura et al., "Corticobasal degeneration presenting with nonfluent primary progressive aphasia: a clinicopathological study", J NEUR SCI, 183(1), 2001, pp. 19-26

Abstract

A 62-year-old woman initially presented with slowly progressive nonfluent aphasia with minimal intellectual involvement. Echolalia and personality change were prominent whereas parkinsonian features and signs suggesting parietal lobe dysfunctions were not present. The patient's language deficit wasconsistent with transcortical motor aphasia. She did not manifest extrapyramidal signs. The patient was diagnosed as having Pick's disease or frontallobe dementia. She died at age 65, 2 years and 9 months following disease onset. Neuropathological findings including cytoskeletal abnormalities, however, were clearly distinct from those of classical Pick's disease and wereconsistent with those reported in corticobasal degeneration (CBD). The distribution of her cortical lesions was accentuated in the frontal language-related area. The clinical manifestations in CBD are diverse, and primary progressive nonfluent aphasia should be considered as an initial symptom of CBD. Neuropathological examination of such patients should include cytoskeletal abnormality studies. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 02:58:01