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Titolo:
The pharmacology underlying pharmacotherapy for tobacco dependence: A focus on bupropion
Autore:
Balfour, DJK;
Indirizzi:
Univ Dundee, Sch Med, Ninewells Hosp, Dept Psychiat, Dundee DD1 9SY, Scotland Univ Dundee Dundee Scotland DD1 9SY t Psychiat, Dundee DD1 9SY, Scotland
Titolo Testata:
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
fascicolo: 1, volume: 55, anno: 2001,
pagine: 53 - 57
SICI:
1368-5031(200101/02)55:1<53:TPUPFT>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
NICOTINE REPLACEMENT THERAPY; SUSTAINED-RELEASE BUPROPION; SMOKING CESSATION; MAJOR DEPRESSION; CIGARETTE-SMOKING; TRIAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Balfour, DJK Univ Dundee, Sch Med, Ninewells Hosp, Dept Psychiat, Dundee DD1 9SY, Scotland Univ Dundee Dundee Scotland DD1 9SY undee DD1 9SY, Scotland
Citazione:
D.J.K. Balfour, "The pharmacology underlying pharmacotherapy for tobacco dependence: A focus on bupropion", INT J CL PR, 55(1), 2001, pp. 53-57

Abstract

Tobacco dependence remains the major preventable cause of early mortality and morbidity in the developed world. The primary reinforcer of the dependence is the nicotine present in tobacco smoke and, for many smokers, successful treatment depends upon breaking this dependence. Until recently, the only specific pharmacotherapy available for tobacco dependence was nicotine replacement therapy (NRT), Although this approach does significantly increase long-term cessation rates, it is by no means a panacea for the many smokers who require help to quit. Recently, a new drug, bupropion (Zyban (R)), has been licensed as an additional pharmacological aid for smoking cessation. This commentary discusses the mechanisms that may account for its efficacy in this indication and considers the impact its introduction may have on the approach of healthcare systems to the treatment of tobacco dependence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 06:36:44