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Titolo:
Implications of hypnotic flexibility on patterns of clinical use
Autore:
Lader, MH;
Indirizzi:
Univ London Kings Coll, Inst Psychiat, London WC2R 2LS, England Univ London Kings Coll London England WC2R 2LS London WC2R 2LS, England
Titolo Testata:
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
, , anno: 2001, supplemento:, 116
pagine: 14 - 19
SICI:
1368-5031(200101):<14:IOHFOP>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
BENZODIAZEPINE HYPNOTICS; REBOUND INSOMNIA; SLEEP DISORDERS; ZALEPLON; ZOLPIDEM; PREVENTION; AGENTS; RISK;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Lader, MH Univ London Kings Coll, Inst Psychiat, London WC2R 2LS, England Univ London Kings Coll London England WC2R 2LS 2R 2LS, England
Citazione:
M.H. Lader, "Implications of hypnotic flexibility on patterns of clinical use", INT J CL PR, 2001, pp. 14-19

Abstract

Insomnia is common among the primary care patient population, 1.3 times more common in women than men, and the prevalence increases with age. Until recently, benzodiazepines (BZs) were the only first-line hypnotics, but withthe availability of non-BZ sleep agents, the management of insomnia is changing. Zolpidem and zopiclone have adverse-effect profiles similar to BZs but lack next-day residual effects with bedtime dosing. Zaleplon is a fast-onset, rapidly eliminated medication that allows for dosing at bedtime or during the night with minimal concern for residual effects. In addition, the BZ-associated problems of tolerance and rebound effects are not evident with long-term zaleplon use. The pharmacokinetic profile of zaleplon has the potential to allow for the treatment of symptoms of sleeplessness when they occur, an approach that could replace the standard practice of always treating in anticipation of a problem.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 13:20:58